Email this article The features of bone exchange at women of eproductive age after bilateral ovariectomy
- Authors: Zazerskaja I.Е.1, Kuznetsova L.V.1, Jakovlev V.G.1, Alexandrova L.А.1, Djachuk А.V.2, Niauri D.А.3, Selkov S.A.3, Dzhumaeva L.M.4
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Affiliations:
- Academician I.P. Pavlov First St. Petersburg State Medical University
- Central Medical and Sanitary Unit No. 1222
- Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
- FGU TsNIRRI Roszdrav
- Issue: Vol 54, No 3 (2005)
- Pages: 28-37
- Section: Original study articles
- URL: https://journals.rcsi.science/jowd/article/view/83446
- DOI: https://doi.org/10.17816/JOWD83446
- ID: 83446
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Abstract
The research of bone exchange in 80 women after bilateral ovariectomy and in 120 patients in natural menopause with duration of estrogen deficiency 4,3±0,6 years and 4,2±0,8 years respectively was performed. There were used the modern techniques of BMD estimation (DEXA) and biochemical markers of bone remodeling - N-MID osteocalcin, Pyrilincs D, Beta-Cross Laps, alkaline phosphatase. The identical orientation of infringements of bone exchange in both groups was revealed. However, at women after ovariectomy the osteoresorption occured more actively, despite on younger age of participants of research that finds reflection in low values of BMD in all parts of skeleton and high occurrence of bone rarefication. The most informative markers of bone exchange, promoting early diagnostics of metabolic osteopathy were revealed.
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##article.viewOnOriginalSite##About the authors
I. Е. Zazerskaja
Academician I.P. Pavlov First St. Petersburg State Medical University
Author for correspondence.
Email: info@eco-vector.com
Russian Federation, 6-8 L'va Tolstogo Str., Saint Petersburg, 197022
L. V. Kuznetsova
Academician I.P. Pavlov First St. Petersburg State Medical University
Email: info@eco-vector.com
Russian Federation, 6-8 L'va Tolstogo Str., Saint Petersburg, 197022
V. G. Jakovlev
Academician I.P. Pavlov First St. Petersburg State Medical University
Email: info@eco-vector.com
Russian Federation, 6-8 L'va Tolstogo Str., Saint Petersburg, 197022
L. А. Alexandrova
Academician I.P. Pavlov First St. Petersburg State Medical University
Email: info@eco-vector.com
Russian Federation, 6-8 L'va Tolstogo Str., Saint Petersburg, 197022
А. V. Djachuk
Central Medical and Sanitary Unit No. 1222
Email: info@eco-vector.com
Russian Federation, Saint Petersburg
D. А. Niauri
Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Email: info@eco-vector.com
Russian Federation, 3 Mendeleevskaya Line, Saint Petersburg, 199034
S. A. Selkov
Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Email: info@eco-vector.com
Russian Federation, 3 Mendeleevskaya Line, Saint Petersburg, 199034
L. M. Dzhumaeva
FGU TsNIRRI Roszdrav
Email: info@eco-vector.com
Russian Federation, Saint Petersburg
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