Pierre Robin Sequence. A Rare Clinical Case

The incidence of fetal malformations has not shown a downward trend. Congenital malformations of the fetus often lead to perinatal mortality and disability of newborns. Fetal ultrasound is still the main method of diagnosing these defects. However, unfortunately, in some cases, anomalies are detected only in the neonatal period. This article describes Pierre Robin sequence, which is a congenital malformation of the maxillofacial region. The malformation is defined as a congenital anomaly characterized by the presence of glossoptosis, micrognathia, and airway obstruction, which leads to various complications. Early recognition and appropriate perinatal management are crucial for improving pregnancy outcomes. Clinical studies conducted in recent years have shown that early prenatal diagnosis and counseling of a geneticist are becoming increasingly important, especially for families with risk factors for having children with malformations. In addition, when comparing clinical cases and scientific data, attention is drawn to the fact that in all cases of children with Pierre Robin syndrome, respiratory failure (of varying severity) due to congenital pneumonia was noted.