Laparoscopic ovarian drilling. The comparison of methods
- Authors: Sibirskaya E.V.1,2,3, Nikiforova P.O.2,3, Egorova A.S.4
-
Affiliations:
- Russian University of Medicine
- Russian Children’s Clinical Hospital, Pirogov Russian National Research Medical University
- Pirogov Russian National Research Medical University
- Peoples’ Friendship University of Russia
- Issue: Vol 74, No 1 (2025)
- Pages: 137-144
- Section: Reviews
- URL: https://journals.rcsi.science/jowd/article/view/291201
- DOI: https://doi.org/10.17816/JOWD633927
- ID: 291201
Cite item
Abstract
The review discusses effective and safe methods of laparoscopic ovarian drilling in clomiphene-resistant women with polycystic ovary syndrome.
Paper search and analysis was completed using the PubMed, Embase, Cochrane Library, and Google Scholar databases. Included are publications made from 1989 to 2024. Authors identified a total of seven cohort studies, two case series, two randomized controlled trials, and one systematic review.
Laparoscopic ovarian drilling helps to overcome anovulatory infertility in clomiphene-resistant women with polycystic ovary syndrome. This method is based on mechanical destruction of follicles and part of the ovarian tissue, which leads to a decrease in androgen levels and an increase in follicle-stimulating hormone levels, resulting in restoration of ovarian function. According to available data, laser vaporization and monopolar electrosurgery are preferred methods. They are considered safe for ovarian tissue and allow for preserving the ovarian reserve. Bipolar electrosurgical techniques, on the other hand, are not recommended due to their high heat levels applied to ovarian tissue and potential impact on follicles.
At present, the leading method of laparoscopic ovarian drilling is under discussion since the research data are controversial.
Full Text
##article.viewOnOriginalSite##About the authors
Elena V. Sibirskaya
Russian University of Medicine; Russian Children’s Clinical Hospital, Pirogov Russian National Research Medical University; Pirogov Russian National Research Medical University
Email: elsibirskaya@yandex.ru
ORCID iD: 0000-0002-4540-6341
SPIN-code: 1356-9252
MD, Dr. Sci. (Medicine), Assistant Professor
Russian Federation, Moscow; Moscow; MoscowPolina O. Nikiforova
Russian Children’s Clinical Hospital, Pirogov Russian National Research Medical University; Pirogov Russian National Research Medical University
Author for correspondence.
Email: pol_nikiforova@mail.ru
ORCID iD: 0000-0001-5046-9016
SPIN-code: 7120-3165
postgraduate student
Russian Federation, Moscow; MoscowAnna S. Egorova
Peoples’ Friendship University of Russia
Email: memater.eas@gmail.com
ORCID iD: 0009-0003-1261-6603
Russian Federation, Moscow
References
- Russian Society of Obstetricians and Gynecologists. Polycystic ovarian syndrome. Clinical recommendations. Moscow: Ministry of Health of the Russian Federation; 2021. (In Russ.) [cited 2024 Aug 20] Available from: https://roag-portal.ru/recommendations_gynecology
- Mayenga JM, Grzegorczyk Martin V, Belaisch-Allart J. Place actuelle du drilling ovarien dans la prise en charge du syndrome des ovaires polykystiques (SOPK) Gynécologie Obstétrique Fertilité & Sénologie. 2011;39(9):518–520. doi: 10.1016/j.gyobfe.2011.07.007
- European Society of Human reproduction and Embryology. International evidence-based guideline for the assessment and management of polycystic ovary syndrome (PCOS). 2023. [cited 2024 Aug 20] Available from: https://www.monash.edu/__data/assets/pdf_file/0003/3379521/Evidence-Based-Guidelines-2023.pdf
- Hafizi L, Amirian M, Davoudi Y, et al. Comparison of laparoscopic ovarian drilling success between two standard and dose-adjusted methods in polycystic ovary syndrome: a randomized clinical trial. Int J Fertil Steril. 2020;13(4):282–288. doi: 10.22074/ijfs.2020.5628
- Sinha P, Chitra T, Papa D, et al. Laparoscopic ovarian drilling reduces testosterone and luteinizing hormone/follicle-stimulating hormone ratio and improves clinical outcome in women with polycystic ovary syndrome. J Hum Reprod Sci. 2019;12(3):224–228. doi: 10.4103/jhrs.JHRS_161_18
- Slouha E, Segal J., White C., et al. Ovarian reserve and hormone alteration following laparoscopic ovarian drilling for polycystic ovarian syndrome: a systematic review. Cureus. 2024;16(6):e62092. EDN: NQFSPG doi: 10.7759/cureus.62092
- Farquhar C, Lilford R, Marjoribanks J, et al. Laparoscopic drilling by diathermy or laser for ovulation induction in anovulatory polycystic ovary syndrome. Cochrane Database System Rev. 2007;(4):CD001122. doi: 10.1002/14651858.CD001122.pub3
- Stefanovic S, Sütterlin M, Gaiser T, et al. Microscopic, macroscopic and thermal impact of argon plasma, diode laser, and electrocoagulation on ovarian tissue. In Vivo. 2023;37(2):531–538. EDN: ZQHJPX doi: 10.21873/invivo.13111.
- Mercorio A, Della Corte L, De Angelis MC et al. Ovarian drilling: back to the future. Medicina (Kaunas). 2022;58(8):1002. EDN: JCMQBS doi: 10.3390/medicina58081002
- Yusubova VR. Laparoscopic ovarian drilling – “for” and “against”. V.F. Snegirev Archives of Obstetrics and Gynecology. 2017;4(2):68–72. EDN: YPHOAT doi: 10.18821/2313-8726-2017-4-2-68-72
- Hendriks ML, van der Valk P, Lambalk CB, et al. Extensive tissue damage of bovine ovaries after bipolar ovarian drilling compared to monopolar electrocoagulation or carbon dioxide laser. Fertil Steril. 2010;93(3):969–975. doi: 10.1016/j.fertnstert.2008.10.046
- Abulafia O, Sherer DM. Angiogenesis of the ovary. Am J Obstet Gynecol. 2000;182:240–246. doi: 10.1016/s0002-9378(00)70519-9
- Carus T, Rackebrandt K. Collateral tissue damage by several types of coagulation (monopolar, bipolar, cold plasma and ultrasonic) in a minimally invasive, perfused liver model. ISRN Surgery. 2011;2011:518924. doi: 10.5402/2011/518924
- Sirmans SM, Pate KA. Epidemiology, diagnosis, and management of polycystic ovary syndrome. J Clin Epidemiol. 2013;6:1–13. doi: 10.2147/CLEP.S37559
- Amer SA, Li TC, Cooke ID. A prospective dose finding study of the amount of thermal energy required for laparoscopic ovarian diathermy. Hum Reprod. 2003;18(8):1693–1698. doi: 10.1093/humrep/deg307
- Fernandez H, Faivre E, Gervaise A, et al. Laparoscopic ovarian drilling using a 5-French bipolar energy probe. Fertil Steril. 2010;94(2):740–741. doi: 10.1016/j.fertnstert.2009.03.048
- Debras E, Fernandez H, Neveu ME, et al. Ovarian drilling in polycystic ovary syndrome: Long term pregnancy rate. Eur J Obstet Gynecol Reprod Biol. 2019;(4):100093. doi: 10.1016/j.eurox.2019.100093
- Kriplani A, Manchanda R, Agarwal N, et al. Laparoscopic ovarian drilling in clomiphene citrate-resistant women with polycystic ovary syndrome. J Am Assoc Gynecol Laparoscop. 2001;8(4):511–518. doi: 10.1016/s1074-3804(05)60613-5
- Balen A, Jacobs H. A prospective study comparing unilateral and bilateral laparoscopic ovarian diathermy in women with the polycystic ovary syndrome (PCOS). Fertil Steril. 1994;62(5):921–925. doi: 10.1016/S0015-0282(16)57051-4
- Daniell JF, Miller W. Polycystic ovaries treated by laparoscopic laser vaporization. Fertil Steril. 1989;51(2):232–236. doi: 10.1016/s0015-0282(16)60482-x
- Naether OG, Fischer R, Weise HC et al. Laparoscopic electrocoagulation of the ovarian surface in infertile patients with polycystic ovarian disease. Fertil Steril. 1993;60(1):88–94. doi: 10.1016/s0015-0282(16)56042-7
- Agadzhanyan ES, Ischenko AI, Dzhibladze TA. Comparative evaluation of ovarian laser drilling in the surgical treatment of women with polycystic ovary syndrome. Sechenov Medical Journal. 2016;4(26):46–52. EDN: ZNLWFD
- Bordewijk EM, Ng KYB, Rakic L, et al. Laparoscopic ovarian drilling for ovulation induction in women with anovulatory polycystic ovary syndrome. Cochrane Database System Rev. 2020;2(2):CD001122. EDN: YIJZVO doi: 10.1002/14651858.CD001122.pub5
- Farquhar C, Brown J, Marjoribanks J. Laparoscopic drilling by diathermy or laser for ovulation induction in anovulatory polycystic ovary syndrome. Cochrane Database System Rev. 2012;(6):CD001122. doi: 10.1002/14651858.CD001122.pub4
- Yu Q, Hu S, Wang Y, et al. Letrozole versus laparoscopic ovarian drilling in clomiphene citrate-resistant women with polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials. Reprod Biol Endocrinol. 2019;17(1):17. EDN: NZEDBB doi: 10.1186/s12958-019-0461-3
- Artini PG, Obino MER, Sergiampietri C, et al. PCOS and pregnancy: a review of available therapies to improve the outcome of pregnancy in women with polycystic ovary syndrome. Expert Rev Endocrinol Metabol. 2018;13(2):87–98. doi: 10.1080/17446651.2018.1431122
- Giampaolino P, De Rosa N, Della Corte L, et al. Operative transvaginal hydrolaparoscopy improves ovulation rate after clomiphene failure in polycystic ovary syndrome. Gynecol Endocrinol. 2018;34(1):32–35. doi: 10.1080/09513590.2017.1323204
Supplementary files
