Evaluation of the effectiveness of innovative methods of focused ultrasound and uterine artery embolization in the treatment of uterine fibroids

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Abstract

BACKGROUND: Uterine fibroids are one of the most common gynecological diseases. The application of innovative techniques such as focused ultrasound ablation and uterine artery embolization has improved the quality of life of many patients. However, despite significant advances in innovative therapies, there is no certainty about the long-term efficacy of focused ultrasound ablation and uterine artery embolization.

AIM: The aim of this study was to compare the efficacy of focused ultrasound ablation and uterine artery embolization treatments of uterine fibroids.

MATERIALS AND METHODS: This study analyzed observations of 112 patients with uterine fibroids. Patients in the first group were treated with focused ultrasound ablation (n = 44). The second group of patients underwent uterine artery embolization (n = 68).

RESULTS: The study groups differed in the reduction of myomatous node sizes one, three, six and 12 months after surgery, depending on the chosen treatment method (p < 0.001). In the first group, fibroid volume decreased by 14% after a month and by 35% after 12 months. In the second group, it decreased by 20% after a month and by 54% after a year.

CONCLUSIONS: Treatment with the uterine artery embolization method reduced fibroid volume by 54%, which is 19% more effective than the focused ultrasound ablation method.

About the authors

Lyudmila V. Kaushanskaya

Rostov State Medical University

Author for correspondence.
Email: ludmila_kaushanskaya0912@mail.ru
ORCID iD: 0000-0002-5065-0066
SPIN-code: 2142-2127

MD, Dr. Sci. (Med.), Professor

Russian Federation, Rostov-on-Don

Zareta M. Gatagazheva

Ingush State University

Email: zaretapoin66@yandex.ru
ORCID iD: 0000-0001-8067-378X
SPIN-code: 4643-6804

MD, Dr. Sci. (Med.), Professor

Russian Federation, Magas

Zukhra K. Uzdenova

H.M. Berbekov Kabardino-Balkarian State University

Email: elifiya@bk.ru
ORCID iD: 0000-0003-0371-2671
SPIN-code: 9296-8074

MD, Dr. Sci. (Med.), Professor

Russian Federation, Nalchik

Malika M. Gatagazheva

Ingush State University

Email: ing_gu@mail.ru
ORCID iD: 0000-0002-6010-0287

MD, Cand. Sci. (Med.), Assistant Professor

Russian Federation, Magas

Khava A. Arsanukaeva

A.A. Kadyrov Chechen State University

Email: arsunukaeva29@gmail.ru
ORCID iD: 0009-0000-7970-2889
Russian Federation, Grozny

Nesredin A. Makhmudov

Rostov State Medical University

Email: vip.nesred@mail.ru
ORCID iD: 0009-0002-4648-869X
Russian Federation, Rostov-on-Don

Darya P. Minigulova

Regional Children’s Clinical Hospital

Email: daryaploxova@mail.ru
ORCID iD: 0009-0008-0726-3352
Russian Federation, Stavropol

References

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  8. Politova AK, Kira EF, Bolomatov NV, et al. Comparative evaluation of combined and isolated applications of high-intensity focused ultrasound and super-selective uterine artery embolization in treatment of patients with uterine fibroids. Journal of Obstetrics and Women’s Diseases. 2022;71(1):71–78. EDN: MREALK doi: 10.17816/JOWD71360

Supplementary files

Supplementary Files
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1. JATS XML
2. Fig. 1. Somatic and gynecological history chart

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3. Fig. 2. Myoma node sizes

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4. Fig. 3. Somatic changes 1, 3, 6 and 12 months after surgery using the focused ultrasound ablation (a) and uterine artery embolization methods (b)

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