Assessment of the severity of menopausal syndrome and psychosomatic peculiarities

Cover Page


Cite item

Full Text

Abstract

Hypothesis/aims of study. Hormonal changes in a woman’s body impacts many systems and organs, therefore the spectrum of menopausal symptoms varies greatly. The current analysis was undertaken to investigate the relationship between the severity of the menopausal syndrome, depending on the personality traits and typological characteristics of women, and the frequency of emotional and affective disorders.

Study design, materials and methods. A study was conducted based on V.A. Almazov National Medical Research Center in which 50 women aged from 44 to 56 years participated, the average age of menopause being 50.4 ± 0.5 years and the average duration of estrogen deficiency 3.3 ± 0.3 years. The study used: 1) Cooperman Index as modified by E.V. Uvarova; 2) Zung Self-Rating Depression Scale; 3) Zung Self-Rating Anxiety Scale; and 4) “The Level of Social Frustration” questionnaire.

Results. Climacteric complaints are most characteristic of married women with a high educational level and a prosperous financial state. When entering menopause (in women with preserved menstrual cycle), endocrine and metabolic complaints came to the fore, weight fluctuations prevailing among all the symptoms. 72% of women reported a weight increase of three and more kilograms, Dyshormonal hyperplasia of the mammary glands and pain in muscles and joints occurred equally often (62%). At the same time, for postmenopausal women, the most characteristic complaints were of the genitourinary syndrome. The neurovegetative syndrome was expressed in all women, regardless of the duration of the estrogen-deficient state and the severity of the menopausal syndrome. When studying the severity of the psycho-emotional syndrome, it was found that patients most often complained of fatigue and decreased performance (99%). Manifestations of depression were not characteristic of women with milder symptoms of menopause, while a high level of anxiety was typical for women with a moderate degree of the climacteric syndrome. For 12% of those women, the depth of depressive disorders corresponded to mild severity. Besides, a high level of anxiety and an average level of depressive manifestations were characteristic of women with severe severity of the menopausal syndrome.

Conclusion. The data obtained show that the more severe the manifestations of the menopausal syndrome, the higher the severity of affective disorders.

About the authors

Yana V. Kostroma

Almazov National Medical Research Center

Author for correspondence.
Email: kostromayana@gmail.com
ORCID iD: 0000-0001-7648-5196
SPIN-code: 1332-2695

MD, Post-Graduate Student. The Department of Obstetrics and Gynecology

Russian Federation, Saint Petersburg

Ekaterina N. Belyaeva

Almazov National Medical Research Center

Email: eksaveta@yandex.ru
SPIN-code: 9499-4814

Researcher. The Research Laboratory of Reproduction and Women’s Health, the Institute of Perinatology and Pediatrics

Russian Federation, Saint Petersburg

Elena L. Khazova

Almazov National Medical Research Center

Email: kamishi77@mail.ru
SPIN-code: 2295-3524

MD, Researcher. The Research Laboratory of Reproduction and Women’s Health, the Institute of Perinatology and Pediatrics

Russian Federation, Saint Petersburg

Lyubov V. Kuznetsova

Almazov National Medical Research Center

Email: krivo73@mail.ru
ORCID iD: 0000-0002-8175-7886
SPIN-code: 5355-0262

MD, PhD, the Head of the Research Laboratory of Reproduction and Women’s Health. The Institute of Perinatology and Pediatrics

Russian Federation, Saint Petersburg

Irina E. Zazerskaya

Almazov National Medical Research Center

Email: zazera@mail.ru
ORCID iD: 0000-0002-8175-7886
SPIN-code: 5873-2280

MD, PhD, DSci (Medicine), the Head of the Department of Obstetrics and Gynecology

Russian Federation, St. Petersburg

References

  1. Балан В.Е., Зайдиева Я.З. Возможности коррекции климактерических расстройств негормональными средствами // Лечащий врач. – 2000. – № 5–6. – C. 24–27. [Balan VE, Zaydieva YZ. Vozmozhnosti korrektsii klimaktericheskikh rasstroystv negormonal’nymi sredstvami. Practitioner. 2000;(5-6):24-27. (In Russ.)]
  2. Вассерман Л.И., Щелкова О.Ю. Медицинская психодиагностика: теория, практика и обучение. – М.: Академия, 2004. – 736 с. [Vasserman LI, Shchelkova OY. Meditsinskaya psikhodiagnostika: teoriya, praktika i obuchenie. Moscow: Akademiya; 2004. (In Russ.)]
  3. Meczekalski B, Katulski K, Podfigurna-Stopa A, et al. Spontaneous endogenous pulsatile release of kisspeptin is temporally coupled with luteinizing hormone in healthy women. Fertil Steril. 2016;105(5):1345-1350.e1342. https://doi.org/10.1016/j.fertnstert.2016.01.029.
  4. Kaur M, Singh H, Ahuja GK. Cardiac performance in relation to age of onset of menopause. J Indian Med Assoc. 2011;109(4):234-237.
  5. Хабибулина М.М., Иорданиди Я.С., Гришина И.Ф., Андреев А.Н. Сравнение дизритмий у женщин с гипертонической болезнью в период пременопаузы и в поздний фертильный период с измененным гормональным фоном в зависимости от вариантов ремоделирования левого желудочка // Кардиология. – 2010. – Т. 50. – № 3. – С. 26–30. [Habibulina MM, Iordanidi YS, Grishina IF, Andreev AN. Comparison of Dysrhythmias in Women with Hypertension in the Period of Premenopause and in Late Fertile Period With Altered Hormonal Background in Dependence on the Variant of Left Ventricular Modeling. Cardiology. 2010;50(3):26-30. (In Russ.)]
  6. Hovelius HEB. Quality of life and hormone therapy in women before and after menopause. Scand J Prim Health Care. 2009;18(2):115-121. https://doi.org/10.1080/ 028134300750019025.
  7. Satoh T, Ohashi K. Quality-of-life assessment in community-dwelling, middle-aged, healthy women in Japan. Climacteric. 2010;8(2):146-153. https://doi.org/10.1080/ 13697130500117961.
  8. Cheng M-H, Hsu C-Y, Wang S-J, et al. The relationship of self-reported sleep disturbance, mood, and menopause in a community study. Menopause. 2008;15(5):958-962. https://doi.org/10.1097/gme.0b013e318160dafa.
  9. Blumel JE, Castelo-Branco C, Binfa L, et al. Quality of life after the menopause: a population study. Maturitas. 2000;34(1):17-23. https://doi.org/10.1016/s0378-5122(99)00081-x.
  10. Rosano GM, Vitale C, Marazzi G, Volterrani M. Menopause and cardiovascular disease: the evidence. Climacteric. 2007;10 Suppl 1:19-24. https://doi.org/10.1080/ 13697130601114917.
  11. Lee HM, Liu MA, Barrett-Connor E, Wong ND. Association of lung function with coronary heart disease and cardiovascular disease outcomes in elderly: the Rancho Bernardo study. Respir Med. 2014;108(12):1779-1785. https://doi.org/10.1016/j.rmed.2014.09.016.
  12. Gibbs Z, Lee S, Kulkarni J. What factors determine whether a woman becomes depressed during the perimenopause? Arch Womens Ment Health. 2012;15(5):323-332. https://doi.org/10.1007/s00737-012-0304-0.
  13. Lai JN, Chen HJ, Chen CM, et al. Quality of life and climacteric complaints amongst women seeking medical advice in Taiwan: assessment using the WHOQOL-BREF questionnaire. Climacteric. 2006;9(2):119-128. https://doi.org/10.1080/13697130600635292.
  14. Elsabagh EEM, Allah ESA. Menopausal symptoms and the quality of life among pre/post menopausal women from rural area in Zagazig city. Life Sci J. 2012;9(2):283-291.
  15. Humeniuk E, Bojar I, Owoc A, et al. Psychosocial conditioning of depressive disorders in post-menopausal women. Ann Agric Environ Med. 2011;18(2):441-445.
  16. Kanadys K, Wiktor-Stoma A, Lewicka M, et al. Predictors of the quality of life of women in peri-menopausal period. Ann Agric Environ Med. 2016;23(4):641-648. https://doi.org/10.5604/12321966.1226860.
  17. Earnest CP, Lavie CJ, Blair SN, Church TS. Heart rate variability characteristics in sedentary postmenopausal women following six months of exercise training: the DREW study. PLoS One. 2008;3(6):e2288. https://doi.org/10.1371/journal.pone.0002288.
  18. Lee YJ, Kim MS, Kim BT, et al. Heart rate variability in metabolic syndrome. J Korean Acad Fam Med. 2002;23(12):1432-1439.
  19. Lee JO, Kang SG, Kim SH, et al. The Relationship between Menopausal Symptoms and Heart Rate Variability in Middle Aged Women. Korean J Fam Med. 2011;32(5):299-305. https://doi.org/10.4082/kjfm.2011.32.5.299.
  20. Neslihan Carda S, Bilge SA, Ozturk TN, et al. The menopausal age, related factors and climacteric symptoms in Turkish women. Maturitas. 1998;30(1):37-40. https://doi.org/10.1016/S0378-5122(98)00041-3.

Supplementary files

Supplementary Files
Action
1. JATS XML
2. Fig. 1. Severity of neurovegetative symptoms, depending on the severity of menopausal syndrome

Download (154KB)
3. Fig. 2. Levels of anxiety and depression, depending on the severity of menopausal syndrome

Download (68KB)

Copyright (c) 2019 Kostroma Y.V., Belyaeva E.N., Khazova E.L., Kuznetsova L.V., Zazerskaya I.E.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies