Email this article Peculiarities of carbohydrate metabolism in pregnant women with bronchial asthma
- Authors: Shapovalova E.A.1, Lavrova O.V.2, Paliychuk A.V.1
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Affiliations:
- Research Institute of Obstetrics, Gynecology, and Reproductology named after D.O. Ott
- Academician I.P. Pavlov First St. Petersburg State Medical University
- Issue: Vol 67, No 5 (2018)
- Pages: 56-61
- Section: Articles
- URL: https://journals.rcsi.science/jowd/article/view/10669
- DOI: https://doi.org/10.17816/JOWD67556-61
- ID: 10669
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Abstract
Hypothesis/aims of study. The aim of this study was to assess the effect of therapy with inhaled glucocorticoids on the course of pregnancy, childbirth, and growth-weight parameters of newborns from mothers with asthma of varying severity.
Study design, materials, and methods. 725 women aged 17 to 43 years with bronchial asthma were examined. In the group of patients with bronchial asthma, 352 patients (48.5%) received glucocorticoids or glucocorticoids + β2-long-acting agonists. Carbohydrate metabolism disorders were found in 45 (6.2%) examined pregnant women, among them 21 women (46.7%) received inhaled glucocorticoids.
Results. The frequency of detection of gestational diabetes mellitus in pregnant women with bronchial asthma, as well as growth-weight parameters of newborns do not differ from the general population.
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##article.viewOnOriginalSite##About the authors
Elena A. Shapovalova
Research Institute of Obstetrics, Gynecology, and Reproductology named after D.O. Ott
Author for correspondence.
Email: e.shapovalova@mail.ru
MD, PhD, Senior Researcher. The Department of Pathology of Pregnancy No. 1
Russian Federation, Saint PetersburgOlga V. Lavrova
Academician I.P. Pavlov First St. Petersburg State Medical University
Email: loverova@bk.ru
MD, PhD, DSci (Medicine), Leading Researcher. The Laboratory of Hereditary Mechanisms of Lung Diseases, the Research Institute of Pulmonology
Russian Federation, Saint PetersburgAnna V. Paliychuk
Research Institute of Obstetrics, Gynecology, and Reproductology named after D.O. Ott
Email: ana.paliichuk@yandex.ru
Resident Physician
Russian Federation, Saint PetersburgReferences
- Купаев В.И., Косарев В.В., Филиппова Т.Ю. Особенности контроля бронхиальной астмы у женщин в период беременности. - Самара: Литфонд, 2004. [Kupaev VI, Kosarev VV, Filippova TY. Osobennosti kontrolya bronkhial’noy astmy u zhenshchin v period beremennosti. Samara: Litfond; 2004. (In Russ.)]
- Распопина Н.А., Шугинин И.О. Бронхиальная астма и беременность: нерешенные вопросы // Клиническая медицина. - 2003. - № 11. - С. 45-48. [Raspopina NA, Shuginin IO. Bronkhial’naya astma i beremennost’: nereshennye voprosy. Klinicheskaya meditsina. 2003;(11):45-48. (In Russ.)]
- Tamasi L, Somoskovi A, Muller V, et al. A population-based case-control study on the effect of bronchial asthma during pregnancy for congenital abnormalities of the offspring. J Asthma. 2006;43(1):81-86. doi: 10.1080/02770900500448803.
- Olesen C, Thrane N, Nielsen GL, et al. A population-based prescription study of asthma drugs during pregnancy: changing the intensity of asthma therapy and perinatal outcomes. Respiration. 2001;68(3):256-261. doi: 10.1159/000050507.
- Чучалин А.Г., Аверьянов А.В., Антонова Н.В., Черняев А.Л. Концепция развития пульмонологической помощи населению Российской Федерации (2004-2008) // Пульмонология. - 2004. - № 2. - С. 34-37. [Chuchalin AG, Aver’yanov AV, Antonova NV, Chernyaev AL. Kontseptsiya razvitiya pul’monologicheskoy pomoshchi naseleniyu Rossiyskoy Federatsii (2004-2008). Pul’monologiia. 2004;(2):34-37. (In Russ.)]
- Лаврова О.В. Клинико-диагностические и организационные подходы к ведению беременных женщин, страдающих бронхиальной астмой, как основа первичной профилактики аллергических заболеваний их детей: Автореф. дис. … д-ра мед. наук. - СПб., 2009. [Lavrova OV. Kliniko-diagnosticheskie i organizatsionnye podkhody k vedeniyu beremennykh zhenshchin, stradayushchikh bronkhial’noy astmoy, kak osnova pervichnoy profilaktiki allergicheskikh zabolevaniy ikh detey. [dissertation]. Saint Petersburg; 2009. (In Russ.)]
- Глобальная инициатива по бронхиальной астме. Глобальная стратегия лечения и профилактики бронхиальной астмы (пересмотр 2017). - М.: Атмосфера, 2017. [Global Initiative for Asthma. Global strategy for asthma management and prevention (update 2017). Moscow: Atmosfera; 2017. (In Russ.)]
- Schatz M, Zeiger RS, Hoffman CP, et al. Intrauterine Growth Is Related to Gestational Pulmonary Function in Pregnant Asthmatic Women. Chest. 1990;98(2):389-392. doi: 10.1378/chest.98.2.389.
- Утешев Д.Б., Крылов И.А., Буюклинская О.В. Бронхиальная астма и беременность: тактика ведения // Проблемы женского здоровья. - 2007. - Т. 2. - № 4. - С. 34-37. [Uteshev DB, Krylov IA, Buyuklinskaya OV. Bronchial asthma and pregnancy: management of the disease. Problemy zhenskogo zdorov’ya. 2007;2(4):34-37. (In Russ.)]
- Wang G, Murphy VE, Namazy J, et al. The risk of maternal and placental complications in pregnant women with asthma: a systematic review and meta-analysis. J Matern Fetal Neonatal Med. 2014;27(9):934-942. doi: 10.3109/14767058.2013.847080.
- Иванов В.А., Сорокина Л.Н., Минеев В.Н., и др. Сочетание бронхиальной астмы и сахарного диабета: синергизм или антагонизм? // Пульмонология. - 2014. - № 6. - С. 103-107. [Ivanov VA, Sorokina LN, Mineev VN, et al. Comorbidity of asthma and diabetes: synergism or antagonism? Russian Pulmonology. 2014;(6):103-107. (In Russ.)]. doi: 10.18093/0869-0189-2014-0-6-103-107.
- Гестационный сахарный диабет. Диагностика, лечение послеродовое наблюдение. Клинические рекомендации. Письмо от 17 декабря 2013 г. № 15-4/10/2-9478. [Gestatsionnyy sakharnyy diabet. Diagnostika, lechenie poslerodovoe nabljudenie. Klinicheskie rekomendacii. Pis’mo ot 17 dekabrja 2013. No. 15-4/10/2-9478. (In Russ.)]. Доступно по: http://zdrav.spb.ru/.
