Email this article 
Post a Comment Epigenes — overgenes level hereditary units
- Authors: Tchuraev R.N1
-
Affiliations:
- Institute of Biology of Ufa Research Scientific Center RAS, Ufa, Republic of Bashkortostanб RF
- Issue: Vol 8, No 4 (2010)
- Pages: 17-24
- Section: Articles
- URL: https://journals.rcsi.science/ecolgenet/article/view/5430
- DOI: https://doi.org/10.17816/ecogen8417-24
- ID: 5430
Cite item
Full Text
Abstract
The theoretical and experimental aspects concept of epigenes are considered. In epigenes part of the heritable information is preserved, coded and trasmitted in generations out of the primary structure of genomic DNA. The behaviour under crosses simples modelic epigenes is demonstrated. The variants of molecular-genetics mechanisms of epigenes and original results of experimental construction artificials epigenes by methods gene-engenering are presented. The ontogenetic and phylogenetic roles of epigene systems are discussed. It has been shown, that even simplest epigene systems can provide key events of ontogeny. The epigenes systems can provide non-Darwinian evolutionary strategy by means of “remember” relatively unsuccesful muves of evolution and preservation reserved variants of ontogeny.
Keywords
About the authors
Rustem N Tchuraev
Institute of Biology of Ufa Research Scientific Center RAS, Ufa, Republic of Bashkortostanб RF
Email: tchuraev@anrb.ru
References
- Голубовский М. Д., 1996. Концепция эпигена 20 лет спустя // Биополимеры и клетка. Т. 12. № 6. С. 5-24.
- Чураев Р. Н., 1975. Гипотеза об эпигене // Исследования по математической генетике / Новосибирск: ИЦиГ СО АН СССР. С. 77-94.
- Чураев Р. Н., 2005. Контуры неканонической теории на- следственности: от генов к эпигенам // Журн. Общ. Биол. Т. 66. № 2. С. 99-122.
- Чураев Р. Н., Ступак И. В., Ступак Е. Э., Галимзянов А. В., 2006 Новое свойство эпигенов: метастабильные эпигеноти- пы // ДАН. Т. 406. № 4. С. 570-573.
- Cline T. W., 1993. The Drosophila sex determination signal: how do flies count to two // Trends in Genet. Vol. 9. № 11. P. 385-390.
- Fedoroff N. V., Schlappi M., Raina R., 1995. Epigenetic regulation of the maize Spm transposon // Bioessays. Vol. 17. № 4. P. 291-297.
- Gardner T. S., Cantor C. R., Collins J. J., 2000. Construction of a genetic toggle switch in Escherichia coli // Nature. Vol. 403. P. 339-342.
- Keyes N. L., Cline T. W., Schedl P., 1992. The primary sex determination signal of Drosophila acts at the level of transcription // Cell. Vol. 68. P. 933-943.
- Lanchmann M., Jablonka E., 1996. The inheritance of phenotypes: an adaptation to fluctuating environments // J. Theor Biol. Vol. 181. P. 1-9.
- Riggs A. D., Porter T. N., 1996. Overview of Epigenetic Mechanisms // Epigenetic mechanism of gene regulation. / Eds. V. W. A. Russo, R. A. Martienssen, A. G. Riggs. New York: Cold Spring Harbor Lab. Press. P. 489-505.
- Spirov A. V., Borovsky M., Spirova O. A., 2002. HOX Pro DB: the functional genomics of hox ensembles // Nucleic Acids Res. Vol. 30. № 1. P. 351-353.
- Tchuraev R. N., 1980. On a stochastic model of a molecular genetic system capable of differentiation and reproduction of the initial state // Biom. J. Vol. 22. № 2. P. 189-194.
- Tchuraev R. N., Stupak I. V., Tropynina T. S., Stupak E. E., 2000. Epigenes: design and construction of new hereditary units // FEBS Lett. Vol. 486. P. 200-202.
- Tchuraev R. N., 2006. General principles of organization and laws of functioning in governing gene networks // Bioinformatics of genome regulation and structure / Eds. N. Kolchanov and R. Hofestaedt. N.Y.: Springer Science Media, Inc. P. 367-377.
Supplementary files
