Association of vitamin D receptor gene with anthropometric measures in komi ethnic group

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Abstract

The relationship between vitamin D receptor gene (VDR) variants with serum 25-OHD3 concentration, body height (BH), body weight (BW), and body composition were examined in Komi ethnic group. The FF genotype associates with higher BW (p=0.002), and lower bone mass (BM, p=0.06) in comparison with the Ff subjects. The BB carriers are shorter than those with Bb genotype (p=0.037); BM is lower among having bb than Bb variants (p=0.025). There were no differences in 25-OHD3 content revealed. The results are consistent with the data obtained in populations from North-Western Europe, but not in tropical and subtropical Caucasians, or in non-Caucasian groups.

About the authors

Andrey Igorevich Kozlov

Moscow State University

Email: dr.kozlov@gmail.com
Ph.D., Senior Scientist, Laboratory of Anthropoecology, Institute and Museum of Anthropology

Galina Grigoryevna Vershubskaya

Moscow State University

Email: galina.ver@gmail.com
Ph.D., Senior Scientist, Laboratory of Anthropoecology, Institute and Museum of Anthropology

Yuliya Aleksandrovna Ateyeva

Perm State Humanitarian-Pedagogical University

Email: Ateewa@yandex.ru
Ph.D. student; Chair of Anatomy, Physiology, and Medicine

Pamela Orr

University of Manitoba

Email: porr@hsc.mb.ca
Dr., Department of Internal Medicine

Linda Larcombe

University of Manitoba

Email: linda.larcombe@gmail.com
Ph.D., Assistant Professor, Department of Internal Medicine

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Copyright (c) 2013 Kozlov A.I., Vershubskaya G.G., Ateyeva Y.A., Orr P., Larcombe L.

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