Sensitive to the effects of environmental factors miR-638 and common diseases

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Abstract

The review provides information on environmental factors affecting the level of miR-638 in humans, potential target genes of this micro-RNA (according to “TargetScanHuman”), diseases and metabolic pathways which potentially regulated miR-638, as well as clinical and experimental data confirming the involvement of miR-638 in the developing a wide range of multifactorial diseases. The data presented in the review expand the understanding of the pathogenesis of various diseases of a multifactorial nature and determine new strategies for studying gene-environment interactions that are important for the formation of health.

About the authors

Aksana N. Kucher

Research Institute of Medical Genetics, Tomsk NRMC

Author for correspondence.
Email: aksana.kucher@medgenetics.ru
ORCID iD: 0000-0003-3824-3641
SPIN-code: 5251-2055
Scopus Author ID: 7004507293
ResearcherId: A-7789-2014
http://www.medgenetics.ru/science/lpg1/personallpg/201590/

Leading Researcher of the Laboratory of Population Genetics, Doctor of Biological Sciences, Professor

Russian Federation, Ushaika Embankment, 10, Tomsk, 634050

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