Case reports: spondylodiscitis and epiduritis after suffering COVID-19
- Authors: Ustenko I.I.1, Kushnir Y.B.1, Amelin A.V.1, Gotovchikov A.А.1, Goranchuk D.V.1, Kulikov A.N.1
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Affiliations:
- Academician I.P. Pavlov First St. Petersburg State Medical University
- Issue: Vol 13, No 1 (2022)
- Pages: 107-117
- Section: Case reports
- URL: https://journals.rcsi.science/clinpractice/article/view/83531
- DOI: https://doi.org/10.17816/clinpract83531
- ID: 83531
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Abstract
Background: The study analyzes a possible rare complication of COVID-19 in the form of spondylodiscitis, including that followed by epiduritis, in patients who survived COVID-19 characterized by severe pneumonia, respiratory failure and systemic inflammatory response syndrome (SIRS).
Clinical case description: Three clinical cases of patients are presented, each of whom had high fever, SIRS with a significant increase in the laboratory markers of inflammation (C-reactive protein (CRP), leukocytosis, erythrocyte sedimentation rate (ESR), fibrinogen, procalcitonin, ferritin), bacterial pneumonia, and severe hemostasis disorders. Despite an antibiotic therapy with broad-spectrum drugs, the development of spondylodiscitis was observed, manifested as acute pain syndrome in the lumbar spine. In the first patient, against the background of a massive antibacterial therapy, revisions of purulent foci, therapy with glucocorticosteroids (GCS), and a surgical treatment, there was significant positive dynamics in the form of the pain syndrome relief. The second patient showed positive dynamics against the background of a conservative antibacterial therapy. The third patient, with a paravertebral abscess at the level of developed spondylodiscitis, received a massive antibiotic therapy combined with GCS, and was operated for the spinal cord decompression.
Conclusion: Spondylodiscitis and epiduritis may be possible complications of COVID-19, including those resulting from the immunosuppressive therapy, which is actively used to stop the cytokine storm.
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##article.viewOnOriginalSite##About the authors
Ilya I. Ustenko
Academician I.P. Pavlov First St. Petersburg State Medical University
Author for correspondence.
Email: ustenko.ilya1997@gmail.com
ORCID iD: 0000-0003-3950-2684
Clinical Resident, first neurology department, MD
Russian Federation, 6/8, Lva Tolstogo street, St. Petersburg, 197022Yana B. Kushnir
Academician I.P. Pavlov First St. Petersburg State Medical University
Email: kushnir.yana2014@yandex.ru
ORCID iD: 0000-0001-7891-9883
Neurologist, first neurology department, MD
Russian Federation, 6/8, Lva Tolstogo street, St. Petersburg, 197022Alexandr V. Amelin
Academician I.P. Pavlov First St. Petersburg State Medical University
Email: avamelin@mail.ru
ORCID iD: 0000-0001-6437-232X
SPIN-code: 2402-7452
MD, PhD, Professor, Neurology department
Russian Federation, 6/8, Lva Tolstogo street, St. Petersburg, 197022Andrey А. Gotovchikov
Academician I.P. Pavlov First St. Petersburg State Medical University
Email: gotovchikov_73@mail.ru
ORCID iD: 0000-0002-8567-6442
neurologist, head of the first neurology department, MD
Russian Federation, 6/8, Lva Tolstogo street, St. Petersburg, 197022Denis V. Goranchuk
Academician I.P. Pavlov First St. Petersburg State Medical University
Email: gordenisval@mail.ru
neurosurgeon, head of the Department of Neurosurgery, MD
Russian Federation, 6/8, Lva Tolstogo street, St. Petersburg, 197022Alexander N. Kulikov
Academician I.P. Pavlov First St. Petersburg State Medical University
Email: ankulikov2005@yandex.ru
ORCID iD: 0000-0002-4544-2967
SPIN-code: 3851-6072
MD, PhD, Professor, deputy chief physician of the clinic for medical part in therapy
Russian Federation, 6/8, Lva Tolstogo street, St. Petersburg, 197022References
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