Clinical course, diagnosis and treatment of gastrointestinal stromal tumors


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Abstract

The article summarizes up-to-date data of the pathogenesis, diagnosis, and treatment conceptions of the stromal tumors of gastrointestinal tract (GIST). Prognostic factors for progression (recurrence or metastasis) for GIST are reported. Special attention is given to immuno-histochemical method of diagnostics and target therapy for these kinds of tumors.

We present the case history of successful operation in a patient with giant intestinal stromal tumor of the stomach, sprouting into neighbouring organs and tissues.

About the authors

Yulyi V. Ivanov

FSBI "Federal Scientific and Clinical Center for Specialized Types of Medical Aid and Medical Technologies" FMBA of Russia

Author for correspondence.
Email: ivanovkb83@yandex.ru

head Department of Surgery, Doctor of Medical Sciences, Professor

Russian Federation, Moscow

References

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  9. Orosz Z., Tornoczky T., Sapi Z. Gastrointestinal stromal tumors: aclinicopathologic and immunohistochemical study of 136 cases. Pathol Oncol Res. 2005. Vol.ll. Pl 1-21.

Supplementary files

Supplementary Files
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2. Fig. 1. Contrast-enhanced abdominal CT. GIST occupies the entire first subphrenic and subcostal space (marked with an arrow), deforming and displacing adjacent organs and tissues.

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3. Fig. 2. CT scan of the chest. High position and deformation of the left dome of the diaphragm (marked with an arrow).

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4. Fig. 3. Operating field. Stage of mobilization of the upper pole of the tumor with the spleen and the tail of the pancreas.

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5. Fig. 4. Operating field. A tumor completely mobilized in a single block with a part of the left dome of the diaphragm, the tail of the pancreas, and the spleen.

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6. Fig. 5. View of the operating field after the completion of the reconstructive stage - the imposition of an esophago-ejuno anastomosis (marked with an arrow).

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7. Fig. 6. Appearance of the removed macro-preparation.

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Copyright (c) 2011 Ivanov Y.V.

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