Confocal laser endomicroscopy of airways problems and prospects


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Abstract

We have described the principle and method of confocal laser endomicroscopy using the system Cellvizio® lung probe Alveoflex (Mauna Kea Technologies, France) to study the distal lower respirato­ry tract in real time. Acynoscopy has been performed in 25 patients aged from 24 to 75 years with differ­ent lung pathology. The problems associated with using of this technology and its potential practical applications are discussed.

About the authors

Alexander V. Averyanov

FGUZ Clinical Hospital № 83 FMBA of Russia

Author for correspondence.
Email: averyanovav@mail.ru

Deputy Chief Physician for Research, Doctor of Medical Sciences

Russian Federation, 28, Orekhovy Boulevard, Moscow

Olesya V. Danilevskaya

FGUZ Clinical Hospital № 83 FMBA of Russia

Email: danless@mail.ru

endoscopist of the Department of Endoscopy, Senior Researcher of the Laboratory of Clinical and Experimental Surgery

Russian Federation, 28, Orekhovy Boulevard, Moscow

Dmitry V. Sazonov

FGUZ Clinical Hospital № 83 FMBA of Russia

Email: dvsazonov@mail.ru

head endoscopy department, candidate of medical sciences

Russian Federation, 28, Orekhovy Boulevard, Moscow

Oleg P. Kuzovlev

FGUZ Clinical Hospital № 83 FMBA of Russia

Email: info@eco-vector.com

Chief Physician, Honored Doctor of the Russian Federation, Doctor of Medical Sciences, Professor

Russian Federation, 28, Orekhovy Boulevard, Moscow

Fedor G. Zabozlaev

FGUZ Clinical Hospital № 83 FMBA of Russia

Email: info@eco-vector.com

Professor of the Department of Pathological Anatomy of the Russian Medical Academy of Postgraduate Education, Head. Pathological Department, Doctor of Medical Sciences

Russian Federation, 28, Orekhovy Boulevard, Moscow

Anna G. Sotnikova

FGUZ Clinical Hospital № 83 FMBA of Russia

Email: info@eco-vector.com

pulmonologist

Russian Federation, 28, Orekhovy Boulevard, Moscow

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Supplementary files

Supplementary Files
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1. JATS XML
2. Fig. 1. Schematic image

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3. Fig. 2. Terminal bronchiole with a pronounced layer of elastic fibers (B).

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4. Fig.2a. Acinoscopy. Terminal bronchiole with a pronounced layer of elastic fibers (1)

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5. Fig. 3. Acinoscopy. The vestibule of the alveoli.

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6. Fig. 4. Acinoscopy in a 73-year-old patient.

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7. Fig. 5.

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8. Fig. 6. Type of pulmonary vessels with CLEM.

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9. Fig. 7. View of the visceral pleura with CLEM.

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10. Fig. 8. Alvestscopy.

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11. Fig. 9.a. Macrophages in the lumen of the alveoli.

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12. Fig. 9. b, c. Alveoscopy. Alveolar macrophages in the lumen of the alveoli

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Copyright (c) 2011 Averyanov A.V., Danilevskaya O.V., Sazonov D.V., Kuzovlev O.P., Zabozlaev F.G., Sotnikova A.G.

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This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

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