A case of rare form of primary cutaneous cd4± small/medium t-cell lymphoma


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Abstract

Primary cutaneous CD4± small/medium T-cell lymphoma is very rare blood disease with usually good prognosis. However similar histology and immunohistochemistry of this pathology with more aggressive T-cells lymphomas, such as mycosis fungoides, make it difficult for pathologist to find the accurate diagnosis. We report about of 40-year-old woman, who came to our clinic with cheek skin lesion.

About the authors

Dmitriy A. Diakonov

Federal State Budgetary Institution of Science Kirov Research Institute of Hematology and Blood Transfusion of the Federal Medical and Biological Agency of Russia

Author for correspondence.
Email: DiakonovDA@rambler.ru

Candidate of Medical Sciences, Senior Researcher, Laboratory of Blood Pathomorphology

Russian Federation, Krasnoarmeyskaya st., 72, Kirov

Nadezhda S. Fedorovskaya

Federal State Budgetary Institution of Science Kirov Research Institute of Hematology and Blood Transfusion of the Federal Medical and Biological Agency of Russia

Email: fednadsf@mail.ru

Candidate of Medical Sciences, Head of the Laboratory of Blood Pathomorphology

Russian Federation, Krasnoarmeyskaya st., 72, Kirov

Alexander S. Luchinin

Federal State Budgetary Institution of Science Kirov Research Institute of Hematology and Blood Transfusion of the Federal Medical and Biological Agency of Russia

Email: glivec@mail.ru

hematologist

Russian Federation, Krasnoarmeyskaya st., 72, Kirov

References

  1. Choi М., Park S.Y., Park H.S. et al. A Case of Primary Cutaneous CD4 Positive Small/medium T Cell Lymphoma. Ann Dermatol 2011; 23 (1): 76-80.
  2. Знаменская Л.Ф., Катунина O.P., Яковлева C.B. Первичные лимфомы кожи. Вестник дерматологии и венерологии 2009; 3: 25-37.
  3. Доронин В.А. Диагностика и лечение первичных Т-клеточных лимфом кожи. Лечащий врач 2007; 5: 47-50.
  4. Leinweber В. Beltraminelli Н., Kerl Н. et al. Solitary small- to medium-sized pleomorphic T-cell nodules of undetermined significance: clinical, histopathological, immunohistochemical and molecular analysis of 26 cases. Dermatology 2009; 219: 42-47.
  5. Macon W.R. Peripheral T-cell lymphomas. He- matol Oncol Clin North Am 2009; 23: 829-842.
  6. Виноградова Ю.Е., Потекаев H.C., Виноградов Д.Л. Лимфомы кожи: диагностика и лечение. М., 2014; с 126-133.
  7. Beltraminelli Н., Leinweber В., Kerl Н. et al. Primary cutaneous CD4± small-/medium-sized pleomorphic T-cell lymphoma: a cutaneous nodular proliferation of pleomorphic T lymphocytes of undetermined significance? A study of 136 cases. Cerroni L Am J Der- matopathol 2009; 31: 317-322.

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Copyright (c) 2015 Diakonov D.A., Fedorovskaya N.S., Luchinin A.S.

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