Glaucoma in Axenfeld–Rieger Syndrome. A Clinical Case
- Authors: Starostina A.V.1, Sidorova A.V.1, Burlakov K.S.1, Khabazova M.R.2
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Affiliations:
- The S. Fyodorov Eye Microsurgery Federal State Institution
- Federal Medico-Biological Agency Federal Research Clinical Center
- Issue: Vol 14, No 3 (2023)
- Pages: 112-118
- Section: Case reports
- URL: https://journals.rcsi.science/clinpractice/article/view/253939
- DOI: https://doi.org/10.17816/clinpract532720
- ID: 253939
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Abstract
Background: Axenfeld–Rieger syndrome is a genetically heterogeneous group of morphogenesis disorders associated with abnormal development of the anterior segment of the eye, teeth, the organ of hearing, and abdominal region. Сongenital glaucoma, which is refractory to standard methods of treatment due to pronounced changes in the structures of the anterior segment of the eyeball and other comorbidities, is frequent manifestation of this syndrome. There are several methods for treating glaucoma in patients with Axenfeld–Rieger syndrome: sinus trabeculectomy, implantation of drainage devices and transscleral cyclocoagulation. Сlinical case description: A patient with congenital glaucoma associated with Axenfeld–Rieger syndrome underwent sinus trabeculectomy with posterior scleral trepanation in the right eye and valve drainage implantation in the left eye at the S. Fyodorov Eye Microsurgery Federal State Institution, Moscow due to the intraocular pressure decompensation. In the postoperative period, an encapsulated cyst around the body of the drainage was detected, and then a revision of the operation area was performed. After the anti-glaucoma operations, the intraocular pressure compensation was achieved in the follow-up period up to 9 months. Conclusion: Depending on the degree of the changes in the anterior chamber angle structures, sinus trabeculectomy or valve drainage implantation are the methods of choice for the surgical treatment aimed at the intraocular pressure compensation and visual function preservation in patients with Axenfeld-Rieger syndrome.
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##article.viewOnOriginalSite##About the authors
Anna V. Starostina
The S. Fyodorov Eye Microsurgery Federal State Institution
Email: anna.mntk@mail.ru
ORCID iD: 0000-0002-4496-0703
SPIN-code: 7106-2347
MD, PhD
Russian Federation, MoscowAlla V. Sidorova
The S. Fyodorov Eye Microsurgery Federal State Institution
Email: sidorova@mntk.ru
ORCID iD: 0000-0001-9384-6117
SPIN-code: 2571-9398
Russian Federation, Moscow
Konstantin S. Burlakov
The S. Fyodorov Eye Microsurgery Federal State Institution
Email: konstantin.burlakow@yandex.ru
ORCID iD: 0000-0002-4383-0325
SPIN-code: 1634-1346
Russian Federation, Moscow
Matgarita R. Khabazova
Federal Medico-Biological Agency Federal Research Clinical Center
Author for correspondence.
Email: rita.khabazova@mail.ru
ORCID iD: 0000-0002-7770-575X
SPIN-code: 2736-9089
Russian Federation, Moscow
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