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Post a Comment Microbiological features of bronchial asthma and chronic obstructive pulmonary disease during remission
- Authors: Smirnova-Saprytskaya M.Y.1, Osipova G.L.1, Ospelnikova T.P.2,3, Danilina G.A.3, Zykov K.A.1
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Affiliations:
- Research Institute of Pulmonology of the Federal Medical-Biological Agency of Russia
- I.I. Mechnikov Research Institute for Vaccines and Sera
- N.F. Gamaleya National Research Center for Epidemiology and Microbiology
- Issue: Vol 9, No 4 (2018)
- Pages: 40-46
- Section: Original Study Articles
- URL: https://journals.rcsi.science/clinpractice/article/view/10709
- DOI: https://doi.org/10.17816/clinpract9440-46
- ID: 10709
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Abstract
Background: Bronchial asthma and chronic obstructive pulmonary disease are currently the fifth leading cause of death in the world. The combination of bronchial asthma and chronic obstructive pulmonary disease seems to be a unique disease resulting from the interaction of genetic, pathological and functional factors.
Aim: Study of clinical and functional parameters, bacterial spectrum in patients with combination of asthma and chronic obstructive pulmonary diseases bronchitis and non-bronchitis types.
Methods: Clinical and functional examination of 69 patients with obstructive respiratory diseases, of which 49 patients with asthma combined with chronic obstructive pulmonary disease of bronchitis and non-bronchitis types. The microbiological spectrum of nasal pharynx induced by sputum was studied.
Results: The following microorganisms were isolated: Staphylococcus (S. aureus, S. epidermidis), Neisseria subflava, Streptococcus (α-haemolyticus, β-haemolyticus), Streptococcus pneumoniae, Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Branhamella catarrhalis, Enterococcus, Haemophilus influenzae, Candida albicans, Aspergillus spp., Actinomyces spp., Cladosporium, Penicillium, and others.
Conclusion: A more pronounced quantitative content and a more diverse microbial landscape leads to a more severe course of the disease asthma combined withchronic obstructive pulmonary disease especially of the bronchitis type.
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##article.viewOnOriginalSite##About the authors
M. Yu. Smirnova-Saprytskaya
Research Institute of Pulmonology of the Federal Medical-Biological Agency of Russia
Author for correspondence.
Email: smirnovamju@yandex.ru
ORCID iD: 0000-0002-4411-8129
науч. сотр. отдела клинических исследований
Russian Federation, 28, Orekchovy Boulevard, Moscow, 115682G. L. Osipova
Research Institute of Pulmonology of the Federal Medical-Biological Agency of Russia
Email: osipovagl@mail.ru
ORCID iD: 0000-0002-0284-7438
SPIN-code: 9023-0095
докт. мед. наук, заведующая отделом клинических исследований
Russian Federation, 28, Orekchovy Boulevard, Moscow, 115682T. P. Ospelnikova
I.I. Mechnikov Research Institute for Vaccines and Sera; N.F. Gamaleya National Research Center for Epidemiology and Microbiology
Email: ospelnikovat@mail.ru
ORCID iD: 0000-0002-1580-6096
SPIN-code: 3375-8393
кандидат медицинских наук, заведующая лабораторией интерферонов; старший научный сотрудник лаборатории цитокинов
Russian Federation, 5a, Malyi Kazennyi lane, Moscow, 105064; 18, Gamalei street, Moscow, 123098G. A. Danilina
N.F. Gamaleya National Research Center for Epidemiology and Microbiology
Email: gala-dan@mail.ru
ст. науч. сотр. лаборатории индикации и ультраструктурного анализа
Russian Federation, 18, Gamalei street, Moscow, 123098K. A. Zykov
Research Institute of Pulmonology of the Federal Medical-Biological Agency of Russia
Email: kirillaz@inbox.ru
ORCID iD: 0000-0003-3385-2632
SPIN-code: 6269-7990
докт. мед. наук, профессор РАН, врио директора
Russian Federation, 28, Orekchovy Boulevard, Moscow, 115682References
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