ADAPTIVE REACTIONS OF THE HUMAN BODY TO HYPOXIA


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Objective: тo study individual differences in the reaction of the human gas transport system to hypoxia using the normobaric hypoxic hypoxia model. Materials and methods. Hypoxia was simulated by breathing an air mixture with a 10% O2 content for 15 minutes, which corresponded to a pO2 of 75 mm Hg. Art. In the initial state, during hypoxic exercise and during the recovery period after exercise, the subjects recorded external respiration indicators: minute respiratory volume (MOD), respiration rate (RR)), blood hemoglobin oxygen saturation, heart rate variability (HRV). Results. With the urgent adaptation of a person to the effects of hypoxic hypoxia, significant changes occur in the functioning of the body's gas transport system: external respiration, the cardiovascular system and the degree of oxygen saturation of hemoglobin. Conclusion. Two types of urgent adaptive reactions were determined depending on the level of oxygen saturation of hemoglobin in blood during hypoxic exposure: “stable” and “unstable”. In these subgroups, multidirectional reactions were found not only of the degree of oxygen saturation of hemoglobin during hypoxia, but also changes in heart rate variability and various levels of overall performance (bibliography: 4 refs).

作者简介

V Golubev

S. M. Kirov Military Medical Academy of the Russian Defense Ministry

Saint Petersburg, Russia

Yu Korolev

S. M. Kirov Military Medical Academy of the Russian Defense Ministry

Saint Petersburg, Russia

N Murgaeva

S. M. Kirov Military Medical Academy of the Russian Defense Ministry

Saint Petersburg, Russia

K Strel'tsova

S. M. Kirov Military Medical Academy of the Russian Defense Ministry

Saint Petersburg, Russia

参考

  1. Korolev Yu. N. et al. On the effect of hypoxia on the respiratory system. In: Baroterapiya v kompleksnom lechenii ranenykh bol'nykh i porazhennykh. Tezisy dokladov 6 Vsearmeyskoy nauchno-prakticheskoy konferentsii (Barotherapy in the complex treatment of wounded and afflicted patients. Proceedings of the 6 All-Army scientific and practical conference). Saint Petersburg: VMedA; 2006: 94-5.
  2. Korolev Yu. N. et al. On the evaluation of types of adaptive reactions under hypoxic load. In: Baroterapiya v kompleksnom lechenii ranenykh bol'nykh i porazhennykh. Tezisy dokladov 6 Vsearmeyskoy nauchno-prakticheskoy konferentsii (Barotherapy in the complex treatment of wounded and afflicted patients. Proceedings of the 6 All-Army scientific and practical conference). Saint Petersburg: VMedA; 2006: 95-6.
  3. Nesterov S. V. Effect of acute experimental hypoxia on cerebral circulation and autonomic regulation of heart rate in humans. Ph. D. thesis. Saint Petersburg; 2004. @@Нестеров С. В. Влияние острой экспериментальной гипоксии на мозговое кровообращение и вегетативную регуляцию сердечного ритма у человека. Автореф. дис. … канд. мед. наук. СПб.; 2004.
  4. Golubev V. N., et al. On the influence of hypoxic training on the parameters of hypoxic stability. In: Baroterapiya v kompleksnom lechenii ranenykh bol'nykh i porazhennykh. Tezisy dokladov 6 Vsearmeyskoy nauchno-prakticheskoy konferentsii (Barotherapy in the complex treatment of wounded and afflicted patients. Proceedings of the 6 All-Army scientific and practical conference). Saint Petersburg: VMedA; 2006: 110-111.

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