Viral hepatitis E

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Abstract

The lecture sets out modern ideas about the etiology of viral hepatitis E, considering its species, physical and chemical properties. The questions of epidemiology are covered, namely, a characteristic of the zones of the spread of the virus, transmission routes, depending on the genotype of the virus, is given. Issues of the pathogenesis of the disease are also given taking into account new data on the virus genotypes. The acute and chronic forms of the course of the disease and extrahepatic manifestations of this infection are described. Their clinical picture, laboratory diagnostic methods, modern principles of therapy and prevention are given.

About the authors

Nikolay I. Kuznetsov

North-West State Medical University named after I.I. Mechnikov

Author for correspondence.
Email: meri-kuz-48-@mail.ru
SPIN-code: 2558-9273

DSc, professor of the Department of Infection Diseases

Russian Federation, 41, Kirochnaya street, Saint-Petersburg, 191015

Elena S. Romanova

North-West State Medical University named after I.I. Mechnikov

Email: E.Romanova@szgmu.ru
SPIN-code: 9435-6838

PhD, Associate Professor of the Department of Infectious Diseases

Russian Federation, 41, Kirochnaya street, Saint-Petersburg, 191015

Galina Yu. Startseva

North-West State Medical University named after I.I. Mechnikov

Email: GalinaStartsevastar661@rambler.ru
SPIN-code: 8392-2950

PhD, Associate Professor of the Department of Infectious Diseases

Russian Federation, 41, Kirochnaya street, Saint-Petersburg, 191015

Natalya V. Zlateva

Polyclinic No. 60 of Pushkin district

Email: zlatevan@mail.ru

Infectious Disease Specialist

Russian Federation, Saint Petersburg

References

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  2. Жданов К.В., Лобзин Ю.В., Гусев Д.А., Козлов К.В. Вирусные гепатиты. – СПб.: Фолиант, 2011. – 304 с. [Zhdanov KV, Lobzin YuV, Gusev DA, Kozlov KV. Virusnyye gepatity. Saint Petersburg: Foliant; 2011. 304 р. (In Russ.)]
  3. Федеральные клинические рекомендации по диагностике и лечению энтеральных гепатитов (гепатит А и гепатит Е) [электронный ресурс]. – СПбГПМУ, 2014. [Federal’nyye klinicheskiye rekomendatsii po diagnostike i lecheniyu enteral’nykh gepatitov (gepatit A i gepatit E) [Elektronnyy resurs]. Saint Petersburg State Pediatric Medical University; 2014. (In Russ.)]. Доступно по: https://mz19.ru/upload/iblock/726/enteral.hepat.pdf. Ссылка активна на 15.11.2019.
  4. European Association for the Study of the Liver. EASL Clinical Practice Guidelines on hepatitis E virus infection. J Hepatol. 2018;68(6):1256-1271. https://doi.org/10.1016/j.jhep.2018.03.005.
  5. Khuroo MS, Khuroo MS, Khuroo NS. Hepatitis E: Discovery, global impact, control and cure. World J Gastroenterol. 2016;22(31):7030-7045. https://doi.org/10.3748/wjg.v22.i31.7030.

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Copyright (c) 2020 Kuznetsov N.I., Romanova E.S., Startseva G.Y., Zlateva N.V.

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