Email this article Acute iucterine hepatitis as a manifestation of severe autoimmune hepatitis
- Authors: Kuznetsov N.I.1, Vasiliev V.V.1, Romanova E.S.1, Startseva G.Y.1, Fedunyak I.P.1,2, Musatov V.B.2,3, Alekseev A.М.2
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Affiliations:
- North-Western State Medical University named after I.I. Mechnikov
- S.P. Botkin Hospital of Clinical Infectious Diseases
- Saint Petersburg State University
- Issue: Vol 27, No 3 (2023)
- Pages: 55-61
- Section: Case report
- URL: https://journals.rcsi.science/RFD/article/view/148263
- DOI: https://doi.org/10.17816/RFD546548
- ID: 148263
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Abstract
In the article, on the example of a clinical case, a variant of the course of severe acute autoimmune hepatitis type II in a 20-year-old woman is analyzed. The prevalence of this disease are presented. Possible types of autoimmune hepatitis course are discussed. The main diagnostic criteria that indicate the likelihood of autoimmune hepatitis and the tactics of managing these patients are described.
This clinical case demonstrates that in the absence of epidemiological, anamnestic data indicating a possible viral or toxic liver damage, it is necessary to think and exclude autoimmune liver damage. It is believed that the level of gamma globulin exceeding more than 1.5 times the upper limit of normal and the absence of viral hepatitis are independent predictors of the presence of autoimmune hepatitis, and the earlier immunosuppressive therapy is started, the more favorable the prognosis of the disease.
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##article.viewOnOriginalSite##About the authors
Nikolai I. Kuznetsov
North-Western State Medical University named after I.I. Mechnikov
Email: meri-kuz-48@mail.ru
ORCID iD: 0000-0001-5378-3860
md, dr. sci. (med.), professor
Russian Federation, 41 Kirochnaya St., Saint Petersburg, 191015Valery V. Vasiliev
North-Western State Medical University named after I.I. Mechnikov
Email: Vcubed@yandex.ru
ORCID iD: 0000-0003-2579-2799
md, dr. sci. (med.), professor
Russian Federation, 41 Kirochnaya St., Saint Petersburg, 191015Elena S. Romanova
North-Western State Medical University named after I.I. Mechnikov
Email: asrom@yandex.ru
ORCID iD: 0000-0002-9887-8561
md, cand. sci. (med.), assistant professor
Russian Federation, 41 Kirochnaya St., Saint Petersburg, 191015Galina Yu. Startseva
North-Western State Medical University named after I.I. Mechnikov
Email: star661@rambler.ru
ORCID iD: 0000-0002-3660-2666
md, cand. sci. (med.), assistant professor
Russian Federation, 41, Kirochnaya street, Saint-Petersburg, 191015Ivan P. Fedunyak
North-Western State Medical University named after I.I. Mechnikov; S.P. Botkin Hospital of Clinical Infectious Diseases
Email: gib30f@mail.ru
ORCID iD: 0000-0002-9918-7762
md, cand. sci. (med.), assistant professor
Russian Federation, 41, Kirochnaya Str. Saint-Petersburg, 191015Vladimir B. Musatov
S.P. Botkin Hospital of Clinical Infectious Diseases; Saint Petersburg State University
Email: doctormusatov@gmail.com
ORCID iD: 0000-0003-2428-3802
md, cand. sci. (med.), assistant professor
Russian Federation, Saint PetersburgAlexander М. Alekseev
S.P. Botkin Hospital of Clinical Infectious Diseases
Author for correspondence.
Email: orit30@yandex.ru
ORCID iD: 0009-0007-9770-343X
Russian Federation, Saint Petersburg
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