Problems of rational medicines use: the situation in Kyrgyzstan

The article discusses the problems of irrational medicines use at the hospital level of the health care system from the perspective of evidence-based medicine and assessment of the adherence of doctors to follow the recommendations from the developed clinical guidelines and protocols of the Kyrgyz Republic.

The study purpose was to analyze the use of medicines and assess the problems of irrational use in hospital-based health facilities in the Kyrgyz Republic.

The material of the study was the sheets of prescriptions from the case histories and the questionnaire on the study of the determinants for using and prescription of medicines by methods of excavation, questionnaires and the analysis of the prescriptions to clinical guidelines and protocols.

The results of our study showed that doctors admit inefficient use of medicines – polypharmacy, prescription of drugs with unproven efficacy and safety, do not follow recommendations from clinical guidelines and protocols under different pretexts. Data from the questionnaires of doctors revealed an inverse correlation between the prescriptions of medicines in accordance with approved national clinical guidelines and protocols and work experience, i.e. the longer the work of the doctor, the less they are guided by the clinical guidelines and protocols (p < 0.05). The results indicate a low level of adherence of doctors to the use of clinical guidelines and protocols, gaps in the awareness of the population on the use of drugs, the lack of a single information system in the sphere of drug circulation.