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Post a Comment Maintenance pharmacotherapy of atopic dermatitis
- Authors: Petrova I.V.1, Omarov N.N.2, Sargsyan M.S.2, Khamroeva S.A.2, Osmanova Z.S.2, Proshin S.N.2
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Affiliations:
- City Hospital of Norilsk No 2, Ministry of Healthcare of Russian Federation
- St. Petersburg State Medical Pediatric University
- Issue: Vol 16, No 1 (2018)
- Pages: 60-63
- Section: Articles
- URL: https://journals.rcsi.science/RCF/article/view/8781
- DOI: https://doi.org/10.17816/RCF16160-63
- ID: 8781
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Abstract
Abstract. Atopic dermatitis (AD) — multifactorial inflammatory disease of skin characterized by pruritus, chronic recurrent process and age-related features of localization and morphology of lesions. This is one of most spread disease of skin up to 40%, meeting in all countries, in both sexes, in different age groups.
The aim. Prevention of severe forms of AD and complications.
Methods. To estimate the degree of atopic dermatitis was used international scale SCORAD (Scoring of Atopic Dermatitis). Results and discussion. At present time the pathogenesis of atopic dermatitis is discussed in terms of heredity resulting in disturbance of skin barrier, deficiency of immune system. The later means the stimulation of Th2-cells resulting in hyperproduction of IgE, hypersensitivity to allergens and nonspecific stimulants, colonization by pathogenic microorganism such as Staphylococcus aureus, Malassezia furfur and so on. The imbalance of autonomous nerve system with increased production of inflammatory mediators is strongly considered in the pathogenesis of atopic dermatitis too.
Conclusion. Considering the multifactoriality of atopic dermatitis the maintenance pharmacotherapy is of particular importance.
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##article.viewOnOriginalSite##About the authors
Inna V. Petrova
City Hospital of Norilsk No 2, Ministry of Healthcare of Russian Federation
Author for correspondence.
Email: doctorinna07@mail.ru
dermatologist, the Head of Division of Dermatology and Venereology
Russian Federation, NorilskNajmudin N. Omarov
St. Petersburg State Medical Pediatric University
Email: onazhmudin@br.ru
6th year student of Medical faculty
Russian Federation, Saint PetersburgMisha S. Sargsyan
St. Petersburg State Medical Pediatric University
Email: sayera.khamroeva@yandex.ru
6th year student of Medical faculty
Russian Federation, Saint PetersburgSaiyora A. Khamroeva
St. Petersburg State Medical Pediatric University
Email: sayera.khamroeva@yandex.ru
6th year student of Medical faculty
Russian Federation, Saint PetersburgZarema S. Osmanova
St. Petersburg State Medical Pediatric University
Email: zarema.osmanova.94@mail.ru
6th year student of Medical faculty
Russian Federation, Saint PetersburgSergei N. Proshin
St. Petersburg State Medical Pediatric University
Email: psnjsn@rambler.ru
Professor of the Department of Pharmacology, Clinical Pharmacology and Pharmacoeconomy
Russian Federation, Saint PetersburgReferences
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