Email this article THYMIC STRESS-INDUCED ATROPHY AND MAST CELLS
- Authors: Polevshchikov AV1, Gusel’nikova VV1
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Affiliations:
- Institute of Experimental Medicine, Saint Petersburg
- Issue: Vol 19, No 1S (2019)
- Pages: 98-100
- Section: Articles
- URL: https://journals.rcsi.science/MAJ/article/view/19345
- ID: 19345
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Abstract
In a study using histological methods, the dynamics of thymic mast cells was evaluated in response to the administration of hydrocortisone to white outbred mice. It was established that 48 hrs after the administration of the hormone, the number of mast cells increases 10-fold, while cells appear at all stages of maturation. In parallel, the level of mast cell degranulation increases. Maturation of mast cells within the thymus and their participation in the regulation of cell migration and remodeling of the extracellular matrix under stress is assumed.
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##article.viewOnOriginalSite##About the authors
A V Polevshchikov
Institute of Experimental Medicine, Saint Petersburg
V V Gusel’nikova
Institute of Experimental Medicine, Saint Petersburg
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- Gusel’nikova VV, Sukhorukova EG, Fedorova EA, et al. A Method for the Simultaneous Detection of Mast Cells and Nerve Terminals in the Thymus in Laboratory Mammals. Neuroscience and Behavioral Physiology. 2015:45(4):371-374.
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