Email this article SOLUBLE FORMS OF IMMUNE CHECK-POINT RECEPTOR PD-1 AND ITS LIGAND PD-L1 IN PERIPHERAL BLOOD OF ONCOLOGIC PATIENTS: CLINICAL AND PATHOLOGIC CORRELATIONS
- Authors: Alferov AA1, Gershtein ES1, Naberezhnov DS1, Goryatcheva IO1, Kushlinskii NE1
-
Affiliations:
- N.N. Blokhin National Medical Research Center of Oncology
- Issue: Vol 19, No 1S (2019)
- Pages: 8-9
- Section: Articles
- URL: https://journals.rcsi.science/MAJ/article/view/19293
- ID: 19293
Cite item
Abstract
The levels proteins of control points of immunity sPD-1, sPD-L1 in serum or plasma of 366 patients with malignant tumors of various nosological forms treated at the N.N. Blokhin National Medical Research Center of Oncology. A correlation of sPD-L1 with the prevalence of the process and the degree of tumor malignancy, as well as a positive correlation with some other tumor markers of blood, was found: VEGF, VEGFR1, MMP-7, MMP-8, TIMP-1.
Keywords
sPD-L1, sPD-1, VEGF, VEGFR1, MMP-7, MMP-8, TIMP-1, sPD-1, sPD-L1, VEGF, VEGFR1, MMP-7, MMP-8, TIMP-1, kidney cancer, ovarian cancer, gastric cancer, bone sarcomas, blood serum, blood plasma
Full Text
##article.viewOnOriginalSite##About the authors
A A Alferov
N.N. Blokhin National Medical Research Center of Oncology
E S Gershtein
N.N. Blokhin National Medical Research Center of Oncology
D S Naberezhnov
N.N. Blokhin National Medical Research Center of Oncology
I O Goryatcheva
N.N. Blokhin National Medical Research Center of Oncology
N E Kushlinskii
N.N. Blokhin National Medical Research Center of Oncology
References
Supplementary files
