Role of the intestinal microbiota in the pathogenesis of multiple sclerosis. Part 2. Gut microbiota as a predisposition factor for the multiple sclerosis development

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Abstract

This part of the review focuses on the proposed involvement of the gut microbiota in the realization of the genetic risk of multiple sclerosis, the formation of the intestinal microbiome in early life, and provides data supporting the hypothesis that aberrant formation of the intestinal microbiota in early life may be a predisposing factor to multiple sclerosis.

About the authors

Irina N. Abdurasulova

Institute of Experimental Medicine

Author for correspondence.
Email: i_abdurasulova@mail.ru
ORCID iD: 0000-0003-1010-6768
SPIN-code: 5019-3940
Scopus Author ID: 22233604700

Cand. Sci. (Biol.), Head of the Pavlov Department of Physiology

Russian Federation, Sаint Petersburg

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2. Figure. Phases of early infant colonization (modified by M.S. Cooperstock and A.J. Zedd [179]) and factors influencing this process. CP, colonization phase; CS, caesarean section; AF, artificial feeding. * Early colonization phases

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