Email this article Method for the prevention of hospital infection in Saint Petersburg
- Authors: Orlov A.V.1,2, Pashkevich A.A.2, Matveev V.S.2,3, Vainer L.B.2, Nachinkina T.A.2, Kraeva L.A.4, Romanyuk F.P.1, Shutova T.A.2, Kuropatenko M.V.5,6, Zhelenina L.A.7
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Affiliations:
- North-Western State Medical University named after I.I. Mechnikov
- St. Olga Children’s Hospital
- Academician I.P. Pavlov First St. Petersburg State Medical University
- Saint-Petersburg Pasteur Institute
- Institute of Experimental Medicine
- Saint Petersburg State Pediatric Medical Universaty
- Saint Petersburg State Pediatric Medical University
- Issue: Vol 22, No 2 (2022)
- Pages: 137-146
- Section: Clinical research
- URL: https://journals.rcsi.science/MAJ/article/view/108748
- DOI: https://doi.org/10.17816/MAJ108748
- ID: 108748
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Abstract
BACKGROUND: Cystic fibrosis is one of the most frequent monogenic diseases, in which, in addition to medical measures, measures for the prevention of the infectious process in the lungs are of great importance, which is provided by a clear organization of the work of any medical institution where patients are observed and where medical and rehabilitation measures are carried out.
AIM: The article describes the experience of the children’s Center in St. Petersburg to prevent cross-infection of patients with cystic fibrosis who have the different luge microbiome.
MATERIALS AND METHODS: The measures taken included a system for monitoring and dynamic control of the seeded pathogenic microflora with a strict separation of patients with cystic fibrosis, who had the isolation and carriage of various pathogens. The system provided for the separation of flows of patients with cystic fibrosis and the prevention of cross-infection, as well as a number of activities related to the disinfection of equipment.
RESULTS: The methods adopted and put into practice have ensured the prevention of cross-infection of patients with cystic fibrosis, excreting various pathogenic bacteria from sputum. The patient management system made it possible to halve the number of hospitalizations of patients with Pseudomonas aeruginosa infection per CF patient per year: from 1.3 in 2001 to 0.6 in 2021, reduce the risk of cross-infection, reduce the number of relapses, hospitalizations and the average length of stay of a patient in a hospital.
CONCLUSIONS: The developed system of assistance has shown its effectiveness and can be implemented in one form or another in the work of cystic fibrosis treatment centers in the Russian Federation.
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##article.viewOnOriginalSite##About the authors
Alexander V. Orlov
North-Western State Medical University named after I.I. Mechnikov; St. Olga Children’s Hospital
Author for correspondence.
Email: orlovcf@yandex.ru
ORCID iD: 0000-0002-2069-7111
SPIN-code: 8287-1405
ResearcherId: O-6746-2014
MD, Cand. Sci. (Med.), Assistant Professor, Department of Pediatrics and Neonatology
Russian Federation, Saint Petersburg; Saint PetersburgAleksandr A. Pashkevich
St. Olga Children’s Hospital
Email: pashkevich_aa@live.ru
ORCID iD: 0000-0002-5151-586X
SPIN-code: 4442-8115
Doctor
Russian Federation, Saint PetersburgVladimir S. Matveev
St. Olga Children’s Hospital; Academician I.P. Pavlov First St. Petersburg State Medical University
Email: voloda2006@gmail.com
ORCID iD: 0000-0002-0081-6638
Assistant Lecturer of the Department of Physical Methods of Treatment and Sports Medicine of the Faculty of Postgraduate Education
Russian Federation, Saint Petersburg; Saint PetersburgLiudmila B. Vainer
St. Olga Children’s Hospital
Email: epid-so@yandex.ru
Epidemiologist
Russian Federation, Saint PetersburgTatiana A. Nachinkina
St. Olga Children’s Hospital
Email: db4@zdrav.spb.ru
Head Doctor
Russian Federation, Saint PetersburgLiudmila A. Kraeva
Saint-Petersburg Pasteur Institute
Email: lykraeva@yandex.ru
ORCID iD: 0000-0002-9115-3250
SPIN-code: 4863-4001
Scopus Author ID: 23473821900
ResearcherId: H-1786-2012
MD, Dr. Sci. (Med.), Professor, Head of the Laboratory of Medical Bacteriology
Russian Federation, Saint PetersburgFedor P. Romanyuk
North-Western State Medical University named after I.I. Mechnikov
Email: pitspb2004@mail.ru
ORCID iD: 0000-0001-8577-2330
SPIN-code: 4446-2428
MD, Dr. Sci (Med.), Professor, Head of Department of Pediatrics and Neonatology
Russian Federation, Saint PetersburgTatiana A. Shutova
St. Olga Children’s Hospital
Email: ta.shutova.spb@yandex.ru
Head of Infectious Diseases Department
Russian Federation, Saint PetersburgMariya V. Kuropatenko
Institute of Experimental Medicine; Saint Petersburg State Pediatric Medical Universaty
Email: kuropatenko.mv@iemspb.ru
ORCID iD: 0000-0003-4214-9412
SPIN-code: 5024-3499
Scopus Author ID: 57222538102
ResearcherId: E-1370-2014
MD, Cand. Sci. (Med.), Leading Research Associate of Ecologic Physiology Department
Russian Federation, Saint Petersburg; Saint PetersburgLiudmila A. Zhelenina
Saint Petersburg State Pediatric Medical University
Email: jelenina@mail.ru
ORCID iD: 0000-0001-8474-5154
SPIN-code: 3893-1637
Scopus Author ID: 6505996764
MD, Dr. Sci. (Med.), Professor
Russian Federation, Saint PetersburgReferences
- Shaginyan IA, Kapranov NI, Chernuxa MYu, et al. Microbial population of lower respiratory tract in children from different age groups with cystic fibrosis. Zh Mikrobiol Epidemiol Immunobiol. 2010;(1):15–20. (In Russ.)
- Polikarpova SV, Zhilina SV, Kondratenko OV, et al. Rukovodstvo po mikrobiologicheskoi diagnostike infektsii dykhatel’nykh putei u patsientov s mukovistsidozom. Moscow; 2019. (In Russ.)
- Totton N, Bradburn M, Hoo ZH, et al. Prospectively predicting Pseudomonas aeruginosa infection’s using routine data from the UK cystic fibrosis register. Health Sci Rep. 2021;4(4):e381. doi: 10.1002/hsr2.381
- Huse HK, Lee MJ, Wootton M, et al. Evaluation of antimicrobial susceptibility testing methods for burkholderia cenocepacia and burkholderia multivorans isolates from cystic fibrosis patients. J Clin Microbiol. 2021;59(12):e0144721. doi: 10.1128/JCM.01447-21
- Asherova IK, Kapranov NI. Mukoviscidoz — mediko-social’naya problema. Moscow; 2013. (In Russ.)
- Mukoviscidoz. Ed. by N.I. Kapranov, N.Yu. Kashirskaya, E.I. Kondratieva. Moscow: Medpraktika-M; 2021. (In Russ.)
- Castellani C, Duff AJA, Bell SC, et al. ECFS best practice guidelines: the 2018 revision. J Cyst Fibros. 2018;17(2):153–178. doi: 10.1016/j.jcf.2018.02.006
- National Consensus “Cystic fibrosis: definitions, diagnostic criteria, therapy”. Ed. by E.I. Kondratieva, N.Yu. Kashirskaya, NI. Kapranov. Moscow; 2016. (In Russ.)
- Chernuxa MYu, Avetisyan LR, Shaginyan IA, et al. Algorithm of microbiological diagnosis of chronic lung infection in patients with cystic fibrosis. Clinical Microbiology and Antimicrobial Chemotherapy. 2014;16(4);312–324. (In Russ.)
- Baranov AA, Namazova-Baranova LS, Kutsev SI, et al. Modern approaches to the management of children with cystic fibrosis. Pediatric Pharmacology. 2022;19(2):153–195. (In Russ.). doi: 10.15690/pf.v19i2.2417
- Baranov AA, Namazova-Baranova LS, Kutsev SI, et al. Cystic fibrosis (cystic fibrosis). Clinical recommendations. Moscow; 2020. (In Russ.)
- SP 158.13330.2014 Buildings and premises of medical organizations. Design rules (with Change N1). Clause 7.2.3.30 [Internet]. Available from: https://www.dokipedia.ru/document/ 5343846?pid=781. Accessed: Jun 2, 2022. (In Russ.)
- Register of patients with cystic fibrosis in the Russian Federation. 2015. Ed. by E.I. Kondratieva, S.A. Krasovsky, A.Yu. Voronkova, et al. Moscow: Medpraktika-M; 2016. 72 p. (In Russ.)
- Register of patients with cystic fibrosis in the Russian Federation. 2017. Ed. by A.Y. Voronkova, E.L. Amelina, N.Yu. Kashirskaya, et al. Moscow: Medpraktika-M; 2019. 68 p. (In Russ.).
- Register of patients with cystic fibrosis in the Russian Federation. 2019. Ed. by N.Yu. Kashirskaya, E.I. Kondratieva, S.A. Krasovsky, et al. Moscow: Medpraktika-M; 2021. 68 p. (In Russ.)
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