NEW ASPECTS OF APPLICATION OF METHYL-4H-THIENO[3,2-b]PYRROLE-5-CARBOXYLATES AND DERIVATIVES IN SYNTHESIS. A REVIEW

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This review summarizes the results of the authors' study of chemical transformations of basic N-substituted methyl 4H-thieno[3,2-b]pyrrolecarboxylate in two main directions concerning the synthesis of new polymers and heterocycles (isoquinolines). In the first part presents data on the synthesis of a series of polyheterofunctionalized polymers based on the first developed from monomeric starting 4N-substituted bis-4H-thieno[3,2-b]-pyrrolomethanes and structurally similar products of cross-coupling (1H-pyrrol-3-ylmethyl)-4H-thieno[3,2-b]-pyrroles, their physicochemical properties were studied, possible step-by-step routes of formation and examples of practical use were proposed. In the second part the results obtained in the course of studying the AlCl3-promoted acylation reactions of N-benzyl- and N-2,3-dimethoxybenzyl-substituted methyl 4H-thieno[3,2-b]-pyrrole carboxylates with acid chlorides of the above-mentioned acids with the isolation of a new topology isoquinolines fused with 4H-thieno[3,2-b]pyrrole and benzene rings are discussed.

作者简介

S. Torosyan

Ufa Institute of Chemistry, Ufa Federal Research Centre of the Russian Academy of Sciences

Z. Nurjakhmetova

Ufa Institute of Chemistry, Ufa Federal Research Centre of the Russian Academy of Sciences

F. Gimalova

Ufa Institute of Chemistry, Ufa Federal Research Centre of the Russian Academy of Sciences

M. Miftakhov

Ufa Institute of Chemistry, Ufa Federal Research Centre of the Russian Academy of Sciences

Email: tsynth@anrb.ru

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