Hybrid Nanosystems Based on an Antibacterial Preparation of Dioxydine and Metal Nanoparticles (Ag and Cu) Included in Biopolymer Cryostructures

Abstract

Cryochemical approaches have been used to synthesize hybrid systems consisting of a cryomodified β form of dioxydine (particle size of 30‒350 nm) and silver or copper nanoparticles (average size of 5‒18 nm). These hybrid composites and their precursors are incorporated into biopolymer cryostructures based on gelatin and calcium alginate. Hybrid composites based on metals and antibacterial drugs are very active in the inhibition of growth of E. coli 52, S. aureus 144, and M. cyaneum 98 in comparison with their separate components.