关于研究对象个体特征对脑脊液电导率指标的影响
- 作者: Vavilov A.Y.1, Pozdeev A.R.1, Khalikov A.А.2, Bayandina S.M.1, Agzamov V.V.2, Pozdeyeva M.A.3
 - 
							隶属关系: 
							
- Izhevsk State Medical Academy
 - Bashkir State Medical University
 - Bauman Moscow State Technical University
 
 - 期: 卷 10, 编号 4 (2024)
 - 页面: 462-473
 - 栏目: 原创研究
 - URL: https://journals.rcsi.science/2411-8729/article/view/288316
 - DOI: https://doi.org/10.17816/fm16178
 - ID: 288316
 
如何引用文章
详细
背景。现代科学文献多次提到,在法医学专家实践中研究脑脊液对于解决诸如致命性颅脑损伤的形成时间和严重程度等重要问题具有前景。电导法作为医学中研究生物对象的客观方法之一,已经使用了相当长的时间。然而,研究对象个体特征对脑脊液电导特性的影响研究明显不足。
研究目的。研究死于颅脑损伤的对象脑脊液的电导特性,分析其与研究对象个体特征的关系,为在确定导致颅脑损伤的外力形成时间的科学研究中推广电导法提供理论依据。
材料与方法。通过实验研究了124例死于颅脑损伤及其后果的尸体脑脊液的电导特性。受试者年龄从17至93岁,损伤形成时间为0至10天。电导测量采用“AKIP RLC 6109”设备 (误差为0.1%),测量频率为0.1 kHz、1 kHz和10 kHz。研究对象的个体特征包括性别、年龄、死亡时间、血液中乙醇的存在及其浓度(‰)。
结果。研究表明,研究对象的性别对脑脊液的电导特性具有显著影响,而对象的年龄和不超过24小时的死亡时间对脑脊液电导特性无显著影响。乙醇浓度的绝对值对脑脊液电导性无显著作用,但乙醇的存在显著改变了脑脊液的电流传导能力。
结论。所研究的个体特征对脑脊液电导特性的影响在开发用于研究颅脑损伤的电导方法时应予以考虑,因为这些因素可能会改变对损伤严重程度和形成时间的评估。
作者简介
Alexey Yu. Vavilov
Izhevsk State Medical Academy
														Email: izhsudmed@hotmail.com
				                	ORCID iD: 0000-0002-9472-7264
				                	SPIN 代码: 3275-3730
																		                								
MD, Dr. Sci. (Medicine), Professor
俄罗斯联邦, IzhevksAlexey R. Pozdeev
Izhevsk State Medical Academy
														Email: apozdeev@bk.ru
				                	ORCID iD: 0000-0002-6302-5219
				                	SPIN 代码: 2242-4828
																		                								
MD, Dr. Sci. (Medicine), Assistant Professor
俄罗斯联邦, IzhevksAirat А. Khalikov
Bashkir State Medical University
														Email: airat.expert@mail.ru
				                	ORCID iD: 0000-0003-1045-5677
				                	SPIN 代码: 1895-7300
																		                								
MD, Dr. Sci. (Medicine), Professor
俄罗斯联邦, UfaSophia M. Bayandina
Izhevsk State Medical Academy
														Email: bay_sofia@mail.ru
				                	ORCID iD: 0009-0005-9888-512X
				                	SPIN 代码: 8604-6691
																		                												                	俄罗斯联邦, 							Izhevsk						
Vadim V. Agzamov
Bashkir State Medical University
							编辑信件的主要联系方式.
							Email: expert.sudmed@yandex.ru
				                	ORCID iD: 0000-0001-9845-2280
				                	SPIN 代码: 2601-5485
																		                												                	俄罗斯联邦, 							Ufa						
Maria A. Pozdeyeva
Bauman Moscow State Technical University
														Email: mashapozdeeva5@gmail.com
				                	ORCID iD: 0009-0007-6403-9886
				                	SPIN 代码: 4731-6769
																		                												                	俄罗斯联邦, 							Moscow						
参考
- Viter VI, Surkov YG, Pozdeev AR, et al. Assessment of craniocerebral trauma severity by specific electrical conductivity spectra of cerebrospinal fluid in the early postmortem period. Problemy ekspertizy v meditsine. 2004;4(3):12–14. EDN: OKGUTZ
 - Gaivoronskaya VI. Crystallographic method of diagnostics of craniocerebral trauma and some pathological conditions in forensic medical practice [dissertation abstract]: 14.00.24. Place of protection: Russian Centre of Forensic Medical Examination. Moscow; 2001. 30 р. (In Russ.)
 - Mainovskaya OA. Forensic medical assessment of craniocerebral trauma in living persons by crystallographic characteristics of cerebrospinal fluid [dissertation abstract]: 14.00.24. Moscow; 2001. 21 р. (In Russ.) EDN: ZLCDDF
 - Chumutin AN. Study of liquor impedance for postmortem assessment of craniocerebral trauma. In: Young science — practical healthcare: Materials of the 92nd final scientific-practical conference of students, residents, postgraduates, young scientists (up to 35 years old) of E.A. Wagner Perm State Medical University, Perm, 15–16 April. Perm: Perm State Medical University named after Academician E.A. Wagner; 2019. Р. 43–44. (In Russ.) EDN: FQOJYH
 - Zuev AL, Mishlanov VYu, Sudakov AI, Shakirov NV. Analysis of ionic, molecular and cellular mechanisms of electrical impedance formation in biological fluids and tissues. Perm scientific center journal. 2014;(2):69–78. EDN: SLQOVJ
 - Pikalyuk VS, Bessalova EY, Tkach VV, et al. Liquor as humoral environment of the organism: Monograph. Simferopol: Arial; 2010. 192 р. (In Russ.) EDN: GWTTCQ
 - Pozdeev AR. Forensic medical evaluation of treatment defects in the premortem period: Monograph. Nizhny Novgorod; 2004. 143 р. (In Russ.) EDN: QLKTZX
 - Dobrovolsky GF. Topographic substantiation of the complex forensic-medical evaluation of the system of liquor circulation in traumatic brain injury [dissertation abstract]: 14.00.24. Place of defence: Moscow State Medical and Dental University named after A.I. Evdokimov. Moscow; 2003. 39 р. (In Russ.)
 - Sarsenov TK. The forensic evaluation of traumatic brain injury. Nauka i Zdravookhranenie. 2013;(4):66–68. EDN: XIKOXL
 - Glantz S. Medico-biological statistics. Transl. from English Yu.A. Danilov, ed. by N.E. Buzikashvili, D.V. Samoilov. Moscow: Praktika; 1999. 459 р. (In Russ.)
 - Naumov ES. Expert system of diagnostics of acute poisoning (for the purposes of forensic medical practice) [dissertation abstract]: 14.00.24. Place of defence: Russian Centre of Forensic Medical Examination. Moscow; 2000. 24 р. (In Russ.)
 - Korotun VN, Lesnikov VV, Viter VI. Changes in synthesised ethanol during storage of cadaver blood under room temperature conditions. Problemy ekspertizy v meditsine. 2013;13(1):9–12. EDN: QZRSCV
 - Khalikov AA, Vavilov AYu. Diagnostics of the age of mechanical trauma in forensic medicine by biophysical methods: Monograph. Izhevsk; 2007. 159 р. (In Russ.) EDN: QLOUDP
 - Permyakov AV, Viter VI. Pathomorphology and thanatogenesis of alcohol intoxication: Monograph. Izhevsk: Ekspertiza; 2002. 91 р. (In Russ.) EDN: XVIWWD
 
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