New method for postmortem determination of alcohol intake
- Authors: Nedugov G.V.1, Nedugov V.G.2
-
Affiliations:
- Samara State Medical University
- Samara International Aerospace Lyceum
- Issue: Vol 6, No 3 (2020)
- Pages: 41-46
- Section: ORIGINAL STUDY ARTICLES
- URL: https://journals.rcsi.science/2411-8729/article/view/122399
- DOI: https://doi.org/10.19048/fm316
- ID: 122399
Cite item
Full Text
Abstract
Background. One of the tasks of the forensic medical examination of acute alcohol intoxication on a corpse is to determine the amount of alcohol taken shortly before death. The disadvantage of existing methods for solving this problem is the need to remove fluid by spinal puncture of the corpse and determine the concentration of ethanol in it. This article shows for the first time the possibility of automated post-mortem determination of the amount of alcohol consumed without knowledge of the parameter ethanol concentration in the spinal fluid. Aim. To develop a mathematical model for postmortem determination of ethanol intake, based on objective parameters of ethanol kinetics and not containing the parameter of ethanol concentration in the spinal fluid, to implement the developed model in the format of a computer program. Material and methods. Regression and simulation mathematical modeling of single-dose ethanol kinetics. Writing the text of a computer program in C#. Results. A set of mathematical models has been developed to enable objective post-mortem determination of the amount of ethanol intake without the need for sampling and chemical-toxicological analysis of the spinal fluid. The set of computational procedures is implemented in the format of the computer program “Alcohol calculator Z 4.0.” Conclusions. The developed method of postmortem determination of ethanol intake and the program “Alcohol calculator Z 4.0” created on its basis are recommended for use in the forensic examination of acute alcohol intoxication on a corpse.
Full Text
##article.viewOnOriginalSite##About the authors
German V. Nedugov
Samara State Medical University
Author for correspondence.
Email: nedugovh@mail.ru
ORCID iD: 0000-0002-7380-3766
PhD, assistant of the Department of forensic medicine of Samara State Medical University
Russian Federation, SamaraVladimir G. Nedugov
Samara International Aerospace Lyceum
Email: megars1@yandex.ru
student of the Samara International Aerospace Lyceum
Russian Federation, SamaraReferences
- Клевно В.А., Максимов А.В., Кучук С.А., Григорьева Е.Н., Заторкина О.Г., Кислов М.А., Крупина Н.А., Лысенко О.В., Романько Н.А., Тарасова Н.В., Плис С.С. Методические рекомендации по судебно-медицинской экспертизе отравления алкоголем. Судебная медицина. 2020;6(1):51–59. [Klevno V.A., Maksimov A.V., Kuchuk S.A., Grigorieva E.N., Zatorkina O.G., Kislov M.A., Krupina N.A., Lysenko O.V., Romanko N.A., Tarasova N.V., Plis S.S. Guidelines for Conducting Forensic Medical Examination in Cases of Alcohol Poisoning. Russian Journal of Forensiс Medicine. 2020;6(1):51–59. (In Russ.)]. https://doi.org/10.19048/2411-8729-2020-6-1-51-59
- Недугов Г.В., Недугов В.Г. Определение давности острых субдуральных гематом по количественному распределению этанола в их содержимом, венозной крови и пузырной моче. Вестник судебной медицины. 2019; 8(4):23–29. [Nedugov G.V., Nedugov V.G. Determination of the age of acute subdural hematomas by quantitative distribution of ethanol in their contents, venous blood and bladder urine. Vestnik sudebnoi meditsiny. 2019;8(4):23–29. (In Russ.) eLIBRARY ID: 42490022]
- Новиков П.И. Экспертиза алкогольной интоксикации на трупе. М.: Медицина, 1967. [Novikov P.I. Ekspertiza alkogolnoi intoksikatsii na trupe [Examination of alcohol intoxication on a corpse]. Moscow: Meditsina, 1967. (In Russ.)]
- Widmark E.M.P. Die theoretischen Grundlagen und die praktische Verwendbarkeit der gerichtlich-medizinischen Alkoholbestimmung. Berlin: Urban & Schwarzenberg, 1932. [Widmark E.M.P. Die theoretischen Grundlagen und die praktische Verwendbarkeit der gerichtlich-medizinischen Alkoholbestimmung [Theoretical bases and practical expediency of forensic medical estimation of alcohol]. Berlin: Urban & Schwarzenberg, 1932. (in German)].
- Rubbens J., Brouwers J., Wolfs K., Adams E., Tack J., Augustijns P. Ethanol concentrations in the human gastrointestinal tract after intake of alcoholic beverages. Eur J Pharm Sci. 2016;86: 91–95. https:// doi.org/10.1016/j.ejps.2016.02.009
- Seidl S., Jensen U., Alt A. The calculation of blood ethanol concentrations in males and females. Int J Legal Med. 2000; 114(1–2):71–77.
- Watson P.E., Watson I.D., Batt R.D. Prediction of blood alcohol concentrations in human subjects. Updating the Widmark Equation. J Stud Alcohol. 1981;42(7):547–556.
- Bielefeld L., Auwärter V., Pollak S., Thierauf-Emberger A. Differences between the measured blood ethanol concentration and the estimated concentration by Widmark’s equation in elderly persons. Forensic Sci Int. 2015;247:23-27. https://doi.org/10.1016/j.forsciint.2014.11.008
Supplementary files
