Role of environmental factors in development of congenital defects

An investigation has been performed in a territory of large industrial region. A complex, environmental impact on development of congenital defects (CD) has been studied. Correlations between CD prevalence and specific anthropogenic factors have been revealed. Relative and attributable risks, which demonstrate a specific effect of a number of adverse environmental factors on CD development and prevalence, have been calculated. Mathematical modeling of association between CD and complex anthropogenic load has been made. The modeling allows to predict CD prevalence among infants at the age under one year in this region, taking into consideration environmental conditions. Researchers have come to conclusion that method of risk assessment should be use to determine factors having a negative impact on reproductive health.