The influence of efferent-quantum methods on the immunity in patients with psoriasis

Aim: to study the influence of plasmapheresis, ultraviolet blood irradiation and their combination on the immunity indices. 142 patients with the progressive stage of extensive psoriasis from the age of 18 to 67 have been investigated. Indices of phagocytosis, cellular and humoral immunity have been studied in dynamics. Elevated levels of immunoglobulin M and A, circulating immune complexes, an imbalance of T-cell immunity as well as increasing neutrophil activity level of protection were revealed. The inclusion of the efferent-quantum methods in the complex treatment of psoriasis contributes to the normalization of T-lymphocyte subpopulations and the absorptive activity of neutrophils, reducing the CEC, immunoglobulin M and A. Better immunological efficacy noted when plasmapheresis and plasmapheresis were used in combination with ultraviolet blood irradiation.

psoriasis, ultraviolet blood radiation, cellular immunity, phagocytic process, immune complexes, immunoglobulins