Interrelation of infringements of microflorae of vaginae and features of change of mechanisms of immunoreactiviti at women with adiposity

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Abstract

We have examined 166 women in the age of 17 to 44 years old. 2 clinical groups were formed: the basic one was 96 women (IMB > 28 kg/ m2) and the control group of 70 women (IМB < 28 kg/m2). Bacteriological and immunological methods were applied while research. It is stated that women with IMB more than 28 kg/ml actually more often had nonspecific vaginitis, bacterial vaginosis, and ureaplasmas, representatives of intestinal group of microorganisms (Enterococcus, E. coli, Klebsiellа, Proteus). Also, women with IMB more than 28 kg/ml actually had higher level of C-peptid; and while making the correlation analysis high positive correlation dependence between a degree of adiposity and antibodies (IgM and IgА) and a degree of adiposity was revealed. Women with IMB more than 28 kg/ml and infringement of vaginas microflorae had 3 times more markers of system inflammatory reaction: C-peptid, IL-8, INF-γ.

About the authors

N I Kan

Ulyanovsk State University

Кафедра семейной медицины и последипломного образованияФакультет последипломного дополнительногои высшего сестринского образования; Ульяновский государственный университет; Ulyanovsk State University

О I Ivandeyeva

State central Clinical Hospital

Гинекологическое отделение МУЗ ЦК МСЧ; State central Clinical Hospital

L N Vanina

State central Clinical Hospital

Гинекологическое отделение МУЗ ЦК МСЧ; State central Clinical Hospital

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