Comparative estimation of influence 3-oxipiridin acetyicysteinate and ambiol on myelosupression cyclophosphamide at mice with  lewis lung carcinoma

O A Kulikov; Куликов О А; А V Siprоv; Сипров А В; V A Kuznetsova; Кузнецова В А

Comparative estimation of influence 3-oxipiridin acetyicysteinate and ambiol on myelosupression cyclophosphamide at mice with lewis lung carcinoma

Authors: Kulikov OA¹, Siprоv АV¹, Kuznetsova VA¹
Affiliations:
1. Medical instituteN.P. Ogarev Mordovsky State University
Issue: No 4 (2009)
Pages: 417-420
Section: Articles
URL: https://journals.rcsi.science/2313-0245/article/view/337910
ID: 337910

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Abstract

It is shown, that in experiment in mice of line С57BL/6 with Lewis lung carcinoma 3-oxipiridinacetylcysteinat (3-OPC) and ambiol reduce myelosupression of the cyclophosphamide, not reducing its antitumor efficiency with respect to primary tumorous knot. The 3-OPC more effectively than ambiol restores erythroid cells of the marrow.

Keywords

3-oksipiridinacetylcisteinat, ambiol, cyclophosphamid, myelosupression

About the authors

O A Kulikov

Medical instituteN.P. Ogarev Mordovsky State University

Email: somvoz@live.ru <mailto:somvoz@live.ru>
Кафедра фармакологии; Медицинский институтМГУ им. Н.П. Огарёва; Medical instituteN.P. Ogarev Mordovsky State University

А V Siprоv

Medical instituteN.P. Ogarev Mordovsky State University

V A Kuznetsova

Medical instituteN.P. Ogarev Mordovsky State University

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