Comparative analisys of ERVWE1 and ERVFRDE1 genes methylation levels in placental tissues in early pregnancy

E G Derevyanchuk; Деревянчук Е Г; N Souren; Souren N; K Lepikhov; Lepikhov K; T P Shkurat; Шкурат Т П

Comparative analisys of ERVWE1 and ERVFRDE1 genes methylation levels in placental tissues in early pregnancy

Authors: Derevyanchuk EG¹, Souren N¹, Lepikhov K¹, Shkurat TP¹
Affiliations:
1. South Federal University
Issue: No S5 (2011)
Pages: 27-33
Section: Articles
URL: https://journals.rcsi.science/2313-0245/article/view/337197
ID: 337197

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Abstract

The search of the causes, underlying pathological processes of the human embryogenesis, has the leading position among studies in the field of Human Reproduction. Therefore we conducted analysis of the epigenetic phenomenon, which regulates expression of the genes, involved in the placenta formation processes. It was suggested, that abnormal methylation levels of human endogenous retroviruses ERVWE1 и ERVFRDE1 genes in chorionic tissue of the placenta fetal part can be associated with pathological course and adverse outcome of the pregnancy.

Keywords

ERVWE1, ERVFRDE1, noncarrying of pregnancy, methylation, genes of human endogenous retroviruses (HERV), ERVWE1, ERVFRDE1, placenta

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Comparative analisys of ERVWE1 and ERVFRDE1 genes methylation levels in placental tissues in early pregnancy

Full Text

Abstract

Keywords

About the authors

E G Derevyanchuk

N Souren

K Lepikhov

T P Shkurat

Supplementary files