Pathomorphological aspects of the embriochorionic complex in the first trimester of pregnancy that complicated by insulin-dependent diabetes mellitus of various severity and stage of compensation

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Abstract

The uterine-placental complex in insulin-dependent diabetes mellitus develops under conditions of preexisting angiopathy and chronic hyperglycemia, affecting its morphofunctional state. Inadequate gestational re-structuring of spiral arteries combined with villous-chorion dyschonia, thrombosis, and intervillous-space incompetence suggest early insufficiency of the embryonal system, thus being predictors of placental insufficiency developing in the second and third trimesters of pregnancy.

About the authors

I A Burenkova

Peoples Friendship University of Russia

Department of Obstetrics and Gynecology with course of Perinatology

I M Ordiynts

Peoples Friendship University of Russia

Department of Obstetrics and Gynecology with course of Perinatology

L R Burganova

Peoples Friendship University of Russia

Department of Obstetrics and Gynecology with course of Perinatology

F G Zabzolaev

Russian Medical Academy of Postgraduate Education

Department of Pathological anatomy

T V Zlatovratskaya

Clinical Hospital № 29

M A Sarmosyan

Clinical Hospital № 29

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