Molecular and cellular determinants in the diagnosis endometrial hyperplasia

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Abstract

We analyzed clinic morphological peculiarities of hyperplastic processes in endometrium of patients during menopausal period and educed molecular and cellular nosotropic determinants of illness; presented evaluation of efficiency of immunihistochemistry of biomolecular markers of proliferation and apoptosis (Ki67, р27, р53 и cyclin E), and also receptor status of endometrium. The author detected relationship between the contents of markers and morphological form of hyperplastic process.

About the authors

B M Shapievsky

Peoples’ Friendship University of Russia

Email: katrin9-99@yandex.ru
Department of obstetrics and gynaecology Medical faculty

E A Pavlova

Peoples’ Friendship University of Russia

Email: katrin9-99@yandex.ru
Department of obstetrics and gynaecology Medical faculty

S E Arakelov

Peoples’ Friendship University of Russia

Email: katrin9-99@yandex.ru
Department of obstetrics and gynaecology Medical faculty

I M Ordiyanc

Peoples’ Friendship University of Russia

Email: ordiyantc@mail.ru
Department of obstetrics and gynaecology Medical faculty

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