Sensitivity of the initiators of acute catarrhal bronchopneumonia in calves to antibiotics and phytobiotics
- Authors: Rodionova N.Y.1, Rudenko P.A.1, Sotnikova E.D.1, Prozorovskiy I.E.1, Shopinskaya M.I.1, Krotova E.A.1, Semenova V.I.1
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Affiliations:
- RUDN University
- Issue: Vol 19, No 2 (2024)
- Pages: 358-369
- Section: Veterinary science
- URL: https://journals.rcsi.science/2312-797X/article/view/315819
- DOI: https://doi.org/10.22363/2312-797X-2024-19-2-358-369
- EDN: https://elibrary.ru/GHBNXR
- ID: 315819
Cite item
Abstract
Antimicrobial activity of antibacterial agents (benzylpenicillin, methicillin, amoxicillin, cefazolin, ceftriaxone, cefquinome, cefepime, gentamicin, tylosin, lincomycin, enrofloxacin, marbofloxacin) and herbal medicines (extracts of Eleutherococcus, Echinacea purpurea and Hypericum perforatum) was studied. The purpose of the research was to determine sensitivity to antibiotics and phytobiotics in microorganisms isolated from bronchoalveolar lavage fluid collected from calves with acute catarrhal bronchopneumonia. Calves with acute catarrhal bronchopneumonia (n = 37) aged 1–3 months were studied in the research. Bronchoalveolar lavage was collected into sterile test tubes from sick calves using silicone sterile catheter. Bacteriological studies were carried out in LLC “Vettest”, using generally accepted methods. Determining the sensitivity of isolated opportunistic microorganisms to antibacterial drugs showed that the vast majority of them have rather low efficiency. It was found that all 115 isolated microorganisms were sensitive only to three antibacterial drugs: fourth-generation cephalosporin antibiotics — cefquinome and cephepime, and third-generation fluoroquinolone antibiotic — marbofloxacin. Of the phytobiotics studied, Hypericum perforatum extract had the most pronounced antimicrobial properties against the main initiators of acute catarrhal bronchopneumonia in the calves. Moreover, it showeda more powerful antimicrobial effect against gram-positive bacteria. This makes it possible to use it widely in complex therapy in calves.
About the authors
Natalya Y. Rodionova
RUDN University
Email: rodionova-nyu@rudn.ru
ORCID iD: 0000-0002-8728-2594
SPIN-code: 8032-5437
Assistant, Agrarian and Technological Institute
6 Miklukho-Maklaya st., Moscow, 117198, Russian FederationPavel A. Rudenko
RUDN University
Author for correspondence.
Email: pavelrudenko76@yandex.ru
ORCID iD: 0000-0002-0418-9918
SPIN-code: 4883-1758
Doctor of Veterinary Sciences, Associate Professor, Department of Veterinary Medicine, Agrarian and Technological Institute
6 Miklukho-Maklaya st., Moscow, 117198, Russian FederationElena D. Sotnikova
RUDN University
Email: sotnikova-ed@rudn.ru
ORCID iD: 0000-0003-1253-1573
SPIN-code: 5511-3661
Candidate of Biological Sciences, Associate Professor, Agrarian and Technological Institute
6 Miklukho-Maklaya st., Moscow, 117198, Russian FederationIvan E. Prozorovskiy
RUDN University
Email: prozorovskiy-ie@rudn.ru
ORCID iD: 0000-0002-1849-3849
Assistant, Department of Veterinary Medicine, Agrarian and Technological Institute,
6 Miklukho-Maklaya st., Moscow, 117198, Russian FederationMarina I. Shopinskaya
RUDN University
Email: mishopinskaya@mail.ru
ORCID iD: 0000-0002-3823-3737
SPIN-code: 2550-4781
Candidate of Veterinary Sciences, Associate Professor, Agrarian and Technological Institute
6 Miklukho-Maklaya st., Moscow, 117198, Russian FederationElena A. Krotova
RUDN University
Email: krotova-ea@rudn.ru
ORCID iD: 0000-0003-1771-6091
SPIN-code: 8847-7220
Candidate of Veterinary Sciences, Associate Professor, Agrarian and Technological Institute
6 Miklukho-Maklaya st., Moscow, 117198, Russian FederationValentina I. Semenova
RUDN University
Email: semenova-vi@rudn.ru
ORCID iD: 0000-0002-1610-1637
SPIN-code: 2152-5318
Candidate of Veterinary Sciences, Associate Professor, Agrarian and Technological Institute
6 Miklukho-Maklaya st., Moscow, 117198, Russian FederationReferences
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