Features of the course of hepatocardial syndrome in cats with hypertrophic cardiomyopathy
- Authors: Sotnikova E.D.1, Petrukhina O.A.1, Byakhova V.M.1, Sibirtsev V.D.2
-
Affiliations:
- RUDN University
- Russian Biotechnological University
- Issue: Vol 18, No 2 (2023)
- Pages: 264-272
- Section: Veterinary science
- URL: https://journals.rcsi.science/2312-797X/article/view/315766
- DOI: https://doi.org/10.22363/2312-797X-2023-18-2-264-272
- EDN: https://elibrary.ru/RYVKKD
- ID: 315766
Cite item
Abstract
The issues of changes in clinical, laboratory and instrumental parameters in cats with hepatocardial syndrome formed against the background of hypertrophic cardiomyopathy were studied. It is known that in high-bred cats with congestive heart failure, secondary hepatopathy can develop and progress. It was shown that hepatocardial syndrome occurs in 33.7 % of cats, out of the total number of patients with hypertrophic cardiomyopathy (n = 83). It has been established that hepatocardial complications in cats are a risk factor for a more severe course of hypertrophic cardiomyopathy. Hepatocardial syndrome in cats with hypertrophic cardiomyopathy is characterized by severe hypothermia, circulatory and respiratory failure. In sick animals, an increase in frequency of breathing during sleep was recorded (33.3±9.3 versus 17.9±1.8 times/min; p < 0.001). Domestic cats with hepatocardial syndrome had a decrease in mean arterial blood pressure (100.2±19.3 versus 107.2±19.1 mm Hg; p < 0.05), sinus tachycardia (200.3±19.6 17.8 times/min; p < 0.001), which leads to a significant decrease in PQ intervals (57.9±9.9 versus 64.9±9.9 ms; p < 0.001) and QT intervals (168.9±17, 2 vs 157.5±18.6 ms; p < 0.001). Sick cats had a significant increase in the time of refilling of capillaries with blood, slowdown in intraventricular conduction, increase in voltage of ventricular and atrial complex on electrocardiograms, expansion of pulmonary vein, significant dilatation of left atrium, extreme concentric hypertrophy of left ventricle, increase in transverse contractility of myocardium of left ventricle and decrease in longitudinal contractility myocardium of left and right ventricles, cardiomyocyte cytolysis syndrome, cholestasis, and hypoalbuminemia
Keywords
About the authors
Elena D. Sotnikova
RUDN University
Author for correspondence.
Email: sotnikova-ed@rudn.ru
ORCID iD: 0000-0003-1253-1573
Candidate of Biological Sciences, Associate Professor, Department of Veterinary Medicine, Agrarian and Technological Institute
6 Miklukho-Maklaya st., Moscow, 117198, Russian FederationOlesya A. Petrukhina
RUDN University
Email: petrukhina-oa@rudn.ru
ORCID iD: 0000-0002-9102-2891
Candidate of Veterinary Sciences, Assistant, Department of Veterinary Medicine, Agrarian and Technological Institute
6 Miklukho-Maklaya st., Moscow, 117198, Russian FederationVarvara M. Byakhova
RUDN University
Email: byakhova-vm@rudn.ru
ORCID iD: 0000-0001-6041-2144
Candidate of Veterinary Sciences, Associate Professor, Department of Veterinary Medicine, Agrarian and Technological Institute
6 Miklukho-Maklaya st., Moscow, 117198, Russian FederationVladimir D. Sibirtsev
Russian Biotechnological University
Email: Sibircev_vd@mail.ru
ORCID iD: 0009-0002-5302-3321
postgraduate student, Department of Veterinary Medicine
11 Volokalamskoe highway, Moscow, 125080, Russian FederationReferences
- Rudenko AA, Rudenko PA, Rudenko VB. Clinical diagnostics of dilated cardiomyopathy in dogs. Vestnik of Ulyanovsk State Agricultural Academy. 2019;(1):62–69. (In Russ.). doi: 10.18286/1816–4501–2019–1–62–69
- Rudenko AA, Vatnikov YA, Rudenko PA, Seleznev SB, Kulikov EV. Endokardioz atrioventrikulyarnykh klapanov serdtsa u sobak [Endocardiosis of atrioventricular heart valves in dogs]. Moscow: PFUR publ.; 2022. (In Russ.).
- Usenko DS, Rudenko AF, Rudenko AA. Biochemical parameters of blood serum of cats in case of cholangiohepatitis. Vestnik of Ulyanovsk State Agricultural Academy. 2019; (4):101–109. (In Russ.). doi: 10.18286/1816–4501–2019–4–101–109
- Vatnikov YA, Kulikov EV, Popova IA, Sakhno NV, Petryaeva AV, Lykhina VS, et al. The change of clinical and biochemical blood indicators at chronic hepatitis of dogs. Bulletin of KrasSAU. 2018;(2):62–69. (In Russ.).
- Popova IA, Vatnikov YA. Dynamics of development anemia in dogs with liver diseases. Veterinary medicine. 2020;(1):16–20. (In Russ.). doi: 10.30896/0042–4846.2020.23.1.16–20
- Vatnikov YA, Sotnikova ED, Byakhova VM, Petrukhina OA, Semenova VI, Rudenko AA. Clinical and pathogenetic characteristics of hepatocardial syndrome in dogs against the background of hepatosis. Veterinary medicine. 2023;(4):40–46. doi: 10.30896/0042–4846.2023.26.4.40–45
- Vatnikov YA, Sotnikova ED, Byakhova VM. Features of development of hepatocardial syndrome in dogs with dilated cardiomyopathy. Veterinary Medicine. 2022;(10):52–57. (In Russ.). doi: 10.30896/0042–4846.2022.25.10.52–57
- Vatnikov Y, Rudenko A, Gnezdilova L, Sotnikova E, Byakhova V, Piven E, et al. Clinical and diagnostic characteristics of the development of hepatocardial syndrome in black and white cows in the early lactation period. Veterinary World. 2022;15(9):2259–2268. doi: 10.14202/vetworld.2022.2259–2268
- Rudenko PA, Vatnikov YA, Rudenko AA, Seleznev SB, Kulikov EV. Patogeneticheskie osobennosti vospalitel’nykh protsessov u koshek [Pathogenetic features of inflammatory processes in cats]. Moscow: PFUR publ.; 2020. (In Russ.).
- Rudenko AA. Citokine profile of blood serum in dogs with mitral valve endocardiosis. Veterinary Medicine. 2017;(10):49–55. (In Russ.).
- Vatnikov YA, Rudenko AA, Rudenko PA Kuznetsov VI, Yagnikov SA. Risk factors for the development of struvite urolithiasis in domestic cats. Vestnik KrasSAU. 2020;(11):122–129. (In Russ.). doi: 10.36718/1819–4036–2020–11–122–129
- Yuldashbaev YA, Vatnikov YA., Rudenko PA, Rudenko AA. Features of the functional state of the organism of sheep under stress. RUDN Journal of Agronomy and Animal Industries. 2022; 17(2):193–202. (In Russ.). doi: 10.22363/2312–797X-2022–17–2–193–202
- Korkots DA, Vatnikov YA, Rudenko AA, Rudenko PA. Pathophysiological characteristics of the development of arterial hypertension in Yorkshire Terriers with alimentary obesity. Agrarian Science. 2021;(9):30–34. (In Russ.). doi: 10.32634/0869–8155–2021–352–9–30–34
- Rudenko AA, Rudenko PA, Vatnikov YA, Yagnikov SA, Kulikov EV, Kuznetsov VI. Informativenes of echocardiographic and hematological screening in cats before general anesthesia. Veterinary Medicine. 2020;(8):53–57. (In Russ.). doi: 10.30896/0042–4846.2020.23.8.53–57
- Rudenko AA, Vatnikov YA, Sotnikova ED, Rudenko PA. Evaluation of linear echocardiographic parameters for endocardiosis of atrioventricular heart valves in dogs. Veterinary Medicine. 2021;(1):53–59. (In Russ.). doi: 10.30896/0042–4846.2021.24.1.53–59
- Sakhno NV, Timokhin OV, Vatnikov YA, Kulikov EV, Strizhakov AA, Gnezdilova LA. The technique for inoculation of infected and pathological material for laboratory animals. Bulletin of KrasSAU. 2017;(3):41–51. (In Russ.).
- Vatnikov YA, Rudenko PA, Rudenko AA, Kulikov EV, Kuznetsov VI, Seleznev SB. Clinical and therapeutic significance of microbiota in purulent-inflammatory processes in animals. International Bulletin of Veterinary Medicine. 2021;(1):286–291. (In Russ.). doi: 10.17238/issn2072–2419.2021.1.286
- Vatnikov YA, Rudenko PA, Bugrov NS, Rudenko AA. Evaluation of the effectiveness of therapy for compensated intestinal dysbacteriosis in cats. Agrarian Science. 2022;(1):24–29. (In Russ.). doi: 10.32634/0869–8155–2022–355–1–24–29
- Rudenko PA, Rudenko VB, Rudenko AA, Khohlova ON, Rzhevskii DI, Kazakov VA, et al. Physicochemical properties and mechanisms of therapeutic action of silicon dioxide nanoparticles. Experimental and Clinical Pharmacology. 2022;85(1):27–31. (In Russ.). doi: 10.30906/0869–2092–2022–85–1–27–31
Supplementary files
