Features of the clinical manifestation of subcompensated intestinal dysbiosis in cats in assessing the effectiveness of its correction

Formation and reproduction of gut microbiome begins at birth, while change in its composition depends mainly on various genetic, nutritional and environmental factors. The article considers the features of clinical manifestation of subcompensated intestinal dysbiosis in cats in assessing the effectiveness of its treatment. The studies were carried out on the basis of Department of Veterinary Medicine, RUDN University, and the clinical work was conducted at private veterinary clinics: ‘Avettura’, ‘Epiona’, ‘In the World with Animals’. Cats were selected for the experiment as they arrived at the initial appointment at veterinary clinics. The diagnosis of suspected intestinal dysbacteriosis was made considering anamnesis, clinical examination, and microbiological tests. The severity of intestinal dysbacteriosis was assessed on the results of clinical and laboratory studies. During the research, clinical and diagnostic approaches for subcompensated intestinal dysbacteriosis in cats were improved. Furthermore, effective ways of its treatment were developed. For subcompensated intestinal dysbacteriosis, administration of ‘Lactobifadol’ probiotic, ‘Vetelakt’ prebiotic and ‘Azoksivet’ immunomodulator showed the greatest therapeutic effect, which led to an overall clinical improvement in 5.50 days. Therapeutic efficacy of B₃ regimen was also clearly evidenced by the positive changes in intestinal microbiota and hematological blood parameters during the pharmacorrection. Improvement of clinical diagnostic approaches, prognosis of intestinal dysbiosis of varying severity and treatment effectiveness in cats require will allow to study intestinal dysbiotic disorders in other animal species.