AGGREGATED EVALUATION OF DIELECTRIC IMPEDANCE SPECTROSCOPY RESULTS BASED ON STATISTICAL PARAMETERS AND HAUSDORFF METRIC

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Abstract

Background. The paper considers a method for the noninvasive diagnosis of breast cancer using dielectric impedance spectroscopy. A method is proposed for the formation of an aggregated assessment of the condition of the breast based on the results of an examination by dielectric impedance spectroscopy, which increases the reliability of the detection of neoplasms. Materials and methods. To evaluate the results of bioimpedance spectroscopy, the following algorithm was developed: based on the results of multiple measurements of the active and reactive components of the complex resistance of the mammary gland in the informative frequency range of 20 Hz – 20 MHz, statistical parameters and the Hausdorff metric of the frequency characteristics of the components of the relative permittivity are calculated, which are normalized by the MINIM method. The aggregated breast condition assessment is formed from normalized estimates of statistical parameters and Hausdorff metrics using the PCA/LOO method. Results. As a result of the study, three objects were ranked according to the volume of heterogeneous inclusions. The results obtained coincided with the experimental data. Conclusions. The use of statistical parameters and the Hasudorf metric allows for a comparative assessment of objects with heterogeneous inclusions, and based on an aggregated assessment, to determine the dynamics of cancer cell development.

About the authors

Kseniya M. Demushkina

Penza State University

Author for correspondence.
Email: riabova.ksenija@yandex.ru

Postgraduate student

(40 Krasnaya street, Penza, Russia)

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