Morphology of nanocrystalline structures of hydroxyapatite based on fractal analysis

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Currently, the global demand for orthopedic implants exceeds 6 million units per year and continues to increase. It is known that human bone is a composite material, the inorganic part of which is formed by calcium phosphates, mainly in the form of hydroxyapatite of non-stoichiometric composition. This fact determines the interest in studying the possibility of using hydroxyapatite-based materials for biomedical purposes, which are similar to the chemical composition of the bone and dental tissues and have high biocompatibility. Research in this area is necessary from both the fundamental perspective for expanding the scope of the method, and in view of development of new materials and studying biological fluids in health and pathology. The work shows that the presence of organic and inorganic additives in the synthesis of hydroxyapatite affects the composition and morphology of the crystals of the resulting compound. The results of analysis, presented in the form of diagrams, allow us to judge the inversely proportional relationship between the crystallization time and the value of the morphological dimension of the hydroxyapatite structures, regardless of the nature of the additive. The results obtained confirm the possibility of using morphological analysis to establish the patterns of formation of hydroxyapatite-based materials and to perform an express assessment of their properties (composition, morphology, degree of crystallinity, nature and concentration of impurities).

Sobre autores

Olga Golovanova

Dostoevsky Omsk State University

Email: golovanoa2000@mail.ru
Dr. Sc., Professor, Head of the Department of Inorganic Chemistry

Vladimir Kiselev

Dostoevsky Omsk State University

Ph. D., Researcher, Inorganic Chemistry Department

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