Comorbidity of chronic heart failure and osteoporosis: literature review
- 作者: Larina V.1, Shcherbina E.1, Dryutova V.1, Larin V.1
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隶属关系:
- Pirogov Russian National Research Medical University
- 期: 卷 14, 编号 2 (2023)
- 页面: 93-104
- 栏目: Reviews
- URL: https://journals.rcsi.science/2221-7185/article/view/146651
- DOI: https://doi.org/10.17816/CS375321
- ID: 146651
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详细
The demographic aging of the population causes an increase in the number of patients with both heart failure (HF) and osteoporosis. This is due to the strengthening of disease-preventive measures, multimorbidity, and presence of comorbid conditions such as senile asthenia. As a result, these pathological conditions can cause serious consequences such as loss of functional and social activity, disability, and high rates of hospitalization and mortality. The article considers the common risk factors of HF and osteoporosis and the leading pathophysiological mechanisms underlying these conditions. Modern ideas about the causes of bone metabolism disorders and their features in patients with HF are discussed. Data on the contribution of systemic and immune inflammation, rennin-angiotensin-aldosterone system activation in the pathogenesis, and progression of HF and osteoporosis are presented. The relationship between low bone mineral density and hemodynamic disorders in patients with HF is also shown. All this is considered in the prospect of distinguishing patients with HF as a risk group for osteoporosis and patients with decreased bone mineral density as having a high cardiovascular risk.
作者简介
Vera Larina
Pirogov Russian National Research Medical University
编辑信件的主要联系方式.
Email: larinav@mail.ru
ORCID iD: 0000-0001-7825-5597
SPIN 代码: 3674-9620
MD, Dr. Sci. (Med.), Professor, department head
俄罗斯联邦, 1 Ostrovityanova Str., 117997, MoscowEkaterina Shcherbina
Pirogov Russian National Research Medical University
Email: esscherbina@inbox.ru
ORCID iD: 0000-0001-8619-8123
SPIN 代码: 6888-7050
department resident
俄罗斯联邦, 1 Ostrovityanova Str., 117997, MoscowValeria Dryutova
Pirogov Russian National Research Medical University
Email: wpolikarpovaaaa@gmail.com
ORCID iD: 0000-0003-4894-7167
SPIN 代码: 5109-6434
department assistant
俄罗斯联邦, 1 Ostrovityanova Str., 117997, MoscowVladimir Larin
Pirogov Russian National Research Medical University
Email: larinvladimir@mail.ru
ORCID iD: 0000-0002-3177-3407
SPIN 代码: 9394-2871
MD, Cand. Sci. (Med.), associate professor
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