Type 2 diabetes mellitus and chronic heart failure: new treatment strategies

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Abstract

The article is devoted to the use of sodium-glucose cotransporter type 2 inhibitors in patients with type 2 diabetes mellitus and chronic heart failure drawing the example of clinical studies with Empagliflozin. Key results of the clinical studies are considered, thanks to which it can be argued that patients with type 2 diabetes mellitus and atherosclerosis-associated diseases, including chronic heart failure, have advantages in predicting cardiovascular outcomes when using hypoglycemic drugs and adding Empagliflozin to standard cardiovascular therapy.

About the authors

Irina Z. Bondarenko

Endocrinology Research Centre

Author for correspondence.
Email: iz_bondarenko@mail.ru
ORCID iD: 0000-0002-5178-6029

D. Sci. (Med.)

Russian Federation, Moscow

Marina G. Bubnova

National Research Center for Therapy and Preventive Medicine

Email: iz_bondarenko@mail.ru
ORCID iD: 0000-0003-2250-5942

D. Sci. (Med.), Prof.

Russian Federation, Moscow

References

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2. Fig. 1. Chronic heart failure in patients with type 2 diabetes mellitus (T2DM): "ominous octet" [11].

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3. Fig. 2. Effects of SGLT2 inhibition.

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