Basic principles of antiplatelet therapy from the perspective of new recommendations


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Abstract

In the presented review, some of the main points of the new European recommendations on the use of double antiplatelet therapy (DAT) and triple antithrombotic therapy in patients with coronary heart disease (CHD) with different approaches to its treatment (conservative, invasive and surgical) are outlined. The positions of acetylsalicylic acid (ASA) are designated as the primary basis of a prophylactic antiplatelet strategy. Attention is paid to a new risk stratification for the calculation of the duration of DAT, recommendations for the proper choice of receptor inhibitors for adenosine diphosphate type P2Y12, for switching between oral inhibitors of P2Y12 and for the duration of DAT in different forms of CHD. The review discusses adherence to therapy with ASA and DAT.

About the authors

M. G Bubnova

National Medical Research Center for Preventive Medicine of the Ministry of Health of the Russian Federation

Email: mbubnova@gnicpm.ru
д-р мед. наук, проф., рук. отд. реабилитации и вторичной профилактики сочетанной патологии с лаб. профилактики атеросклероза и тромбоза 101990, Russian Federation, Moscow, Petroverigskii per., d. 10, str. 3

V. P Mihin

Kursk State Medical University of the Ministry of Health of the Russian Federation

д-р мед. наук, проф., зав. каф. внутренних болезней № 2 305041, Russian Federation, Kursk, ul. Karla Marksa, d. 3

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