Correlation of quality of life and significant seasonal fluctuations blood pressure in the morning hours in patients with arterial hypertension

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Abstract

The aim of the present study was to identify the relationship between the quality of life of patients with arterial hypertension (AH) and the degree of seasonal fluctuations in blood pressure (BP) in the morning hours in these patients, as well as to trace the seasonal dynamics of the average morning levels of blood pressure in this group of patients. We analyzed the database of various studies carried out in our center between 1996 and 2011, which contained data 953 ambulatory BP monitoring (ABPM). ABPM data were analyzed in patients with hypertension, without serious comorbidities, who conducted blood pressure monitoring on a weekly background of antihypertensive therapy. Results of the study. It has been shown that diastolic blood pressure (DBP) in the morning (at) was the highest in winter (83.5±13.7 mm Hg), at the lowest - in summer (80.2±11.5 mm Hg), which was typical of the seasonal dynamics of blood pressure generally. The systolic blood pressure (SBP) was characterized by the highest level of the fall in blood pressure (133.3±18.7 mm Hg). The smallest - in the winter (131,8 B±17,6 mm Hg). The differences between the seasons are not reliable. When analyzing the results by using generalized linear models (Generalized Linear Models) and calculating the Fisher's exact test (F) The following patterns were identified. Intensity of seasonal increases in blood pressure (compared with the average level of blood pressure) was inversely related to the level of social support of friends, colleagues, relatives (Scale VI Quality of Life Questionnaire) (for F DBP was 4.29 (p<0.04), for SBP - F=11.29 (p<0.001)). In addition, men and older people, seasonal fluctuations in the garden are more pronounced (F=5.01 (p<0.03) and F=5,05 (p<0.03), respectively). Conclusion. Thus, the severity of seasonal fluctuations outpatient SBP and DBP was inversely related to social support of patients with hypertension. In addition to seasonal fluctuations in the garden was a significant age and gender. Seasonal dynamics of DBP was typical: BP levels were maximal in winter, in the summer - are minimal. At the same time, with the SDP of the highest level of blood pressure was observed in the fall, the lowest - in the winter.

About the authors

G. F Andreeva

State Research Center for Preventive Medicine of the Ministry of Health of the Russian Federation

Email: gandreeva@gnicpm.ru
канд. мед. наук, ст. науч. сотр. лаб. применения амбулаторных диагностических методов в профилактике хронических неинфекционных заболеваний ФГБУ ГНИЦ ПМ 101990, Russian Federation, Moscow, Petroverigsky per., d. 10, str. 3

A. D Deev

State Research Center for Preventive Medicine of the Ministry of Health of the Russian Federation

Email: adeev@gnicpm.ru
канд. физ.-мат. наук, рук. лаб. биостатистики ФГБУ ГНИЦ ПМ 101990, Russian Federation, Moscow, Petroverigsky per., d. 10, str. 3

V. M Gorbunov

State Research Center for Preventive Medicine of the Ministry of Health of the Russian Federation

Email: vgorbunov@gnicpm.ru
д-р мед. наук, проф., рук. лаб. применения амбулаторных диагностических методов в профилактике хронических неинфекционных заболеваний ФГБУ ГНИЦ ПМ 101990, Russian Federation, Moscow, Petroverigsky per., d. 10, str. 3

O. V Molchanova

State Research Center for Preventive Medicine of the Ministry of Health of the Russian Federation

Email: gandreeva@gnicpm.ru
канд. мед. наук, вед. науч. сотр. лаб. применения амбулаторных диагностических методов в профилактике хронических неинфекционных заболеваний ФГБУ ГНИЦ ПМ 101990, Russian Federation, Moscow, Petroverigsky per., d. 10, str. 3

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