Predictors of development of cardiovascular events after stenting of coronary arteries at patients with obesity

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Abstract

Aim. Study predictors of development of cardiovascular events after stenting of coronary arteries at patients with the coronary heart disease (CHD) with obesity.Material and methods. The study population included 186 (54,4±9,1 years) patients with coronary artery disease (CAD) and obesity undergoing percutaneous coronary intervention (PCI) with bare-metal stenting and at least 12 months of follow. The all patients research main and additional metabolic risk factors and epicardial fat thickness (EFT) with determination of echocardiography. Cardiovascular events were registered at 58 (31%) patients. The lipoprotein a - LP(а), leptin, blood glucose, interlaken-6, diastolic arterial pressure and index prevalence of coronary atherosclerosis on Gensini scale became predictors of cardiovascular events. The indicator of EFT showed interrelation with risk of a cardiovascular events. Conclusion. Determination of additional parameters of a lipid profile, carbohydrate metabolism, pro-inflammatory activity of plasma, neurohumoral activity of visceral fat and degree of epicardial adiposity is necessary for the purpose of formation of group of high risk of complications and carrying out prevention of risk factors before carrying out a coronary revascularization.

About the authors

N. G Veselovskaya

SCIENTIFIC RESEARCH INSTITUTE of integrated problems of cardio-vascular diseases SB RAMS, Kemerovo; Altai Krai cardiological clinic, Barnaul

Email: nadezhda100@rambler.ru
канд. мед. наук, ст. науч. сотр. отд. мультифокального атеросклероза ФГБУ НИИ КПССЗ СО РАМН, врач КГБУЗ АККД

G. A Chumakova

SCIENTIFIC RESEARCH INSTITUTE of integrated problems of cardio-vascular diseases SB RAMS, Kemerovo; Altai State Medical University of the Ministry of health of Russia, Barnaul

Email: g.a.chumakova@mail.ru
д-р мед. наук, проф. каф. госпитальной и поликлинической терапии ГБОУ ВПО АГМУ, вед. науч. сотр. отд. мультифокального атеросклероза НИИ КПССЗ

O. V Gritsenko

SCIENTIFIC RESEARCH INSTITUTE of integrated problems of cardio-vascular diseases SB RAMS, Kemerovo; Altai State Medical University of the Ministry of health of Russia, Barnaul

Email: qritzenko.olesia@mail.ru
аспирант каф. госпитальной и поликлинической терапии ГБОУ ВПО АГМУ; науч. сотр. отд. мультифокального атеросклероза НИИ КПССЗ

N. G Mironova

Altai Krai cardiological clinic, Barnaul

Email: g.a.chumakova@mail.ru
зав. отд-нием КГБУЗ АККД

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