Email this article The possibilities of usage of ivabradin (Coraxan) in elderly and senile patients with the syndrome of polymorbidity
- Authors: Ilnitskij A.N1,2, Proshchaev K.I1,2, Priadko L.V2
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Affiliations:
- Institute of postgraduate education of FMBA of Russia, Moscow
- ANO Scientific medical center «Gerontology», Moscow
- Issue: Vol 4, No 4 (2013)
- Pages: 33-36
- Section: Articles
- URL: https://journals.rcsi.science/2221-7185/article/view/45042
- DOI: https://doi.org/10.26442/CS45042
- ID: 45042
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Abstract
The article presents the results of own researches, according to which the syndrome of polymorbidity in people of elderly and senile age in the face of contraindications to use of b-adrenoblockers, may be an alternative to the appointment of the drug ivabradin (Coraxan). He contributes to a significant decrease of the heart rate, improve anginose status and quality of life. In terms of prospects of the further introduction of the drug into clinical practice seems advisable to identify his protective neuroimmunoendocrine effects, which, probably, will allow to expand the indications to its application.
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##article.viewOnOriginalSite##About the authors
A. N Ilnitskij
Institute of postgraduate education of FMBA of Russia, Moscow; ANO Scientific medical center «Gerontology», Moscow
Email: a-ilnitski@yandex.ru
д-р мед. наук, проф., зав. каф. терапии и патологии пожилого возраста
K. I Proshchaev
Institute of postgraduate education of FMBA of Russia, Moscow; ANO Scientific medical center «Gerontology», Moscow
Email: prashchayeu@yandex.ru
д-р мед. наук, проф., дир. АНО НИМЦ «Геронтология»
L. V Priadko
ANO Scientific medical center «Gerontology», Moscow
Email: wrach73@mail.ru
науч. сотр. отд. клин. геронтологии
References
- Лазебник Л.Б. Полиморбидность у пожилых. Сердце. 2007; 7:25–7.
- Прощаев К.И., Ильницкий А.Н., Постникова Л.И. и др. Клиническая патология полиморбидности в гериатрической практике. Успехи геронтологии. 2011; 2: 285–9.
- Прощаев К.И., Ильницкий А.Н., Кветной И.М., Князькин И.В. Изменения эндотелия при сердечно - сосудистой патологии у пожилых. Ч. 1. Сигнальные молекулы и функции эндотелия. Клин. медицина. 2007; 85 (11): 9–13.
- Bores J.S, Fox K, Jaillon P, Lerebours G. Antianginal and antiischemic effects of ivabradine, an I (f) inhibitor, in stable angina: a randomized, double - blind, multicentered, placebo - controlled trial. Circulation 2003; 107 (6): 817–23.
- Ivabradine: in adults with chronic heart failure with reduced left ventricular ejection fraction. Am J Cardiovasc Drugs 2012; 12 (6): 415–26.
- Лопатин Ю.М. Ингибитор If - каналов ивабрадин в лечении больных хронической сердечной недостаточностью: время дебатов прошло, пора действовать. Рос. кардиол. журн. 2012; 4: 6–11.
