Left atrial myxoma — difficulties in diagnosis, determination of treatment tactics in an older patient: clinical case

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Abstract

BACKGROUND: Myxoma is one of the most common benign neoplasms of the heart. The most characteristic localization is the inter-atrial septum in the region of the oval window. Clinically, myxoma can be represented by obstructive, thromboembolic, non-specific symptoms. However, the absence of pathognomonic signs is the reason for the late diagnosis and treatment.

CLINICAL CASE DESCRIPTION: A 78-year-old female patient was hospitalized at the department of cardiology for examination, correction of therapy, and determination of indications for diagnostic coronary angiography. During a routine examination, echocardiographic data revealed a formation in the left atrial (LA) cavity. To clarify the diagnosis and determine the treatment strategies, the patient underwent magnetic resonance imaging of the heart with gadolinium, which verified this formation as an LA myxoma measuring 10×12 mm. Considering the age of the patient, the presence of concomitant pathology, and absence of complications of myoxoma (obstructive and thromboembolic), the patient was further observed.

CONCLUSION: LA myxomas have clinical manifestations; however, quite often, they are accidental findings in echocardiographic studies. Surgical removal of the tumor is currently the main treatment method. The absolute indications for surgical treatment are large tumors and presence of complications (embolic and obstructive). However, in older patients, who, according to imaging methods, have small tumors and concomitant somatic diseases, dynamic follow-up appears suitable to assess the progression of tumor growth and determine the timing of surgical treatment.

About the authors

Sofya V. Alekseeva

Mechnikov North-West State Medical University

Email: naf200372@gmail.com
ORCID iD: 0000-0002-1811-1185

5th year student

Russian Federation, Saint-Petersburg

Alexey A. Liseev

Mechnikov North-West State Medical University

Email: alex_liseev2001@mail.ru
ORCID iD: 0000-0003-4311-1109

5th year student

Russian Federation, Saint-Petersburg

Natalya S. Tretyakova

Mechnikov North-West State Medical University

Author for correspondence.
Email: TretyakovaNS@list.ru
ORCID iD: 0000-0003-3844-1429
SPIN-code: 5464-1240

MD, Cand. Sci. (Med.), department assistant

Russian Federation, 47 Piskarevskij Ave., 195067, St. Petersburg

References

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Supplementary files

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2. Fig. 1. Myxoma of the left atrium according to the data of the echographic study (circled in red).

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3. Fig. 2. Four-chamber projection. Floating formation in the lower third of the interatrial septum (myxoma is marked in red).

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4. Fig. 3. Short axis is at the level of the atria (myxoma contour is outlined in green).

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