胸骨BCG骨炎儿童病例：临床观察系列
- 作者: Stalmakhovich V.N.1, Dyukov A.A.2, Teschuk R.A.2
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隶属关系:
- Irkutsk State Medical Academy of Postgraduate Education
- Irkutsk Regional Children’s Hospital
- 期: 卷 14, 编号 4 (2024)
- 页面: 531-540
- 栏目: Case reports
- URL: https://journals.rcsi.science/2219-4061/article/view/280634
- DOI: https://doi.org/10.17816/psaic1851
- ID: 280634
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背景。自1921年以来，BCG疫苗作为抗结核免疫的重要手段已在全球范围内广泛应用。然而，这种疫苗的使用存在引发各种并发症的风险，其中 BCG骨炎 是一种罕见但极具威胁性的并发症。据观察，胸骨是该病最常见的发生部位之一。
研究目的。提高医学界对 BCG骨炎 这种罕见但严重疾病的认识和了解。该文章对多学科医生具有重要意义，因为大多数患者初次就诊时并非直接寻求外科医生的帮助。
材料与方法。2009年至2023年间，在伊尔库茨克儿童地区临床医院外科二科共治疗 8例胸骨BCG骨炎病例，占所有BCG骨炎病例的 29.63%。患者特征性别: 6名男性，2名女性；平均年龄: 9.12个月（范围为5至14个月）。术前诊断主要方法：多排螺旋CT（MSCT）胸部检查；软组织超声检查（补充诊断）。在手术前，1例患者出现并发症，表现为胸前壁瘘管及广泛创面。
结果。根据临床和流行病学标准，在 8例患者中，7例 确诊为 BCG骨炎。确诊方法：术后组织学及细胞学检查；1例通过分子遗传学方法完全验证诊断。手术治疗方法：根治性清创术 为主要手术方式。术后管理：确诊为 BCG骨炎 后，患者被转至结核病防治中心接受特异性化疗。随访结果：未发现疾病复发。
结论。BCG骨炎 是抗结核疫苗接种中最罕见但最严重的并发症之一。及时的 根治性手术治疗 和 特异性化疗 可在 100% 的病例中实现完全康复。
作者简介
Victor N. Stalmakhovich
Irkutsk State Medical Academy of Postgraduate Education
Email: Stal.irk@mail.ru
ORCID iD: 0000-0002-4885-123X
SPIN 代码: 9042-5092
MD, Dr. Sci. (Medicine), Professor
俄罗斯联邦, IrkutskAndrei A. Dyukov
Irkutsk Regional Children’s Hospital
Email: duk.hir@mail.ru
ORCID iD: 0000-0001-6007-1298
MD, Cand. Sci. (Medicine)
俄罗斯联邦, IrkutskRoman A. Teschuk
Irkutsk Regional Children’s Hospital
编辑信件的主要联系方式.
Email: teschuk@yandex.ru
ORCID iD: 0009-0007-4069-2258
俄罗斯联邦, Irkutsk
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