Salmonellosis osteomyelitis of the pelvic bones in adolescent: a case report

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Abstract

Salmonellosis osteomyelitis is a rare form of extraintestinal salmonellosis in children that occurs against the background of sepsis. This article presents observation of salmonellosis osteomyelitis in a previously healthy 17-year-old patient. The patient experienced pain in the right lower limb with restriction of its mobility. Magnetic resonance imaging revealed bone-destructive changes in the lumbosacral spine. Thrombocytopenia progressed to 60×109/l. In the oncohematologic domain, secondary character of thrombocytopenia was established, and iliac–lumbar muscle abscesses were found. The child was transferred to a surgical hospital, and sepsis, osteomyelitis of the right lateral mass of the sacrum, right-sided sacroiliitis, abscess of the right iliopsoas muscle, bilateral polysegmental pneumonia, and bilateral pleuritic were diagnosed. Surgical opening and drainage of the abscess of the lumbosacral muscle was performed. The study of abscess secretion detected Salmonella gr. B Chester, a resistance gene to penicillins, cephalosporins, and carbapenems. Therapy with off-label ciprofloxacin at 400 mg with pronounced positive dynamics. Cases of treatment of patients with atypical forms of salmonellosis show the need for further accumulation of experience, modification of treatment protocols, and verification of pathogens at an early stage for greater therapy effectiveness.

About the authors

Ivan А. Andreev

N.N. Burdenko Voronezh State Medical University

Author for correspondence.
Email: iwan-andr.andreev@yandex.ru
ORCID iD: 0000-0002-2072-1425
SPIN-code: 8957-4676
Russian Federation, Voronezh

Dmitry A. Baranov

N.N. Burdenko Voronezh State Medical University; Regional Children’s Clinical Hospital No. 2

Email: mitargan_br@mail.ru
ORCID iD: 0000-0002-1300-8672
SPIN-code: 3307-1994

MD, Cand. Sci. (Medicine), Associate Professor

Russian Federation, Voronezh; Voronezh

Vladimir A. Vecherkin

N.N. Burdenko Voronezh State Medical University; Regional Children’s Clinical Hospital No. 2

Email: vecherkinva@mail.ru
ORCID iD: 0000-0002-6024-6585
SPIN-code: 1042-0689

MD, Dr. Sci. (Medicine), Professor

Russian Federation, Voronezh; Voronezh

Vladimir A. Ptitsyn

N.N. Burdenko Voronezh State Medical University; Regional Children’s Clinical Hospital No. 2

Email: lena.chudya@mail.ru
ORCID iD: 0000-0002-7917-4681
SPIN-code: 4043-9631

MD, Cand. Sci. (Medicine), Associate Professor

Russian Federation, Voronezh; Voronezh

Pavel V. Koryashkin

N.N. Burdenko Voronezh State Medical University; Regional Children’s Clinical Hospital No. 2

Email: koryashkinpavel@mail.ru
ORCID iD: 0000-0002-6447-5035
SPIN-code: 8749-6829

MD

Russian Federation, Voronezh; Voronezh

Victor М. Gagloev

Belgorod State University

Email: Gagloev_VM@mail.ru
ORCID iD: 0009-0008-7913-4904
SPIN-code: 8707-8240

MD, Cand. Sci. (Medicine)

Russian Federation, Belgorod

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Supplementary files

Supplementary Files
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1. JATS XML
2. Fig. 1. Ultrasound of the iliopsoas muscle in two projections. Arrows indicate mass formation

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3. Fig. 2. MRI of the retroperitoneal space. Arrows indicate abscesses in the iliopsoas and piriformis muscles on the right

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4. Fig. 3. Chest CT scan (cross section)

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5. Fig. 4. Dynamics of the inflammatory process according to temperature and C-reactive protein

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6. Fig. 5. MR image of the pelvis on day 12 of the disease: а — osteomyelitis of the wing of the right iliac bone (arrow); b — osteomyelitis of the right lateral mass of the sacrum. Right-sided sacroiliitis (arrows)

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7. Fig. 6. MR image of the pelvis on day 26 of the disease: a — relief of manifestations of osteomyelitis of the right lateral mass of the sacrum, right-sided sacroiliitis; b — decreased size of right iliac muscle abscesses, retroperitoneal soft tissue infiltration on the right side

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