Comparative assessment of acceptability of the prognostic scales in predicting the risk of interhospital evacuation of newborns

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Abstract

BACKGROUND: The safety of interhospital transfer of newborns remains one of the most important issues of emergency neonatology. Assessment of risks associated with transfer is the basic concern of pre-transport preparation.

AIM: This study aimed to assess and compare the predictive value of the KSCHONN, National Therapeutic Intervention Scoring System (NTISS), and TRIPS scales in predicting the risks associated with the interhospital transfer of newborns.

MATERIALS AND METHODS: The cohort study included data from 604 visits of the transport team. The KSHONN, NTISS, and TRIPS scales were used in the assessments, the therapeutic actions of the transport team during transfer were evaluated, and mortality during the first day after assessments was analyzed. The area under the receiver operating characteristic curve (AUC ROC) was calculated for the KSCHONN, NTISS, and TRIPS scales in relation to the therapeutic actions of the transport team and first-day mortality.

RESULTS: The predictive values of the KSHONN and TRIPS scales for additional infusion reflected AUC ROC values of 0.877 (0.436–1.317) and AUC ROC 0.889 (0.468–1.311), respectively. The AUC ROC value for predicting catecholamine dose adjustment or appointment and correction of ventilation for all three scales was less than 0.8. The predictive value of all three scales in the prediction of death on the day after the assessment of the transport team is high, and the TRIPS scale had the highest AUC ROC [0.988 (0.977–0.999)], which was significantly higher than that for the NTISS scale 0.875 (0.790–0.959) (p = 0.004). The KSHONN scale demonstrated a better predictive value for daily mortality [0.984 (0.861–1.003)] in comparison with NTISS (p = 0.001). The risk ratio of the daily mortality in the group of patients with an assessment of 9–4 points according to KSHONN in comparison with patients with an assessment of 6–8 points was 17.73 (0.88–355.8).

CONCLUSIONS: The evaluated scales predict patient death within a day after the assessment of the transport team with good accuracy, and the KSHONN and TRIPS scales predict the need for additional infusion during transfer. However, none of the scales predict other actions of the team associated with the deterioration of the patient’s condition during transfer with the required accuracy.

About the authors

Rustam F. Mukhametshin

Regional Children’s Clinical Hospital; Ural State Medical University

Author for correspondence.
Email: rustamFM@yandex.ru
ORCID iD: 0000-0003-4030-5338
SPIN-code: 4206-3303

Cand. Sci. (Med.), Anesthesiologist-Resuscitator

Russian Federation, 32, S. Deryabinoi st., Yekaterinburg, 620149; Yekaterinburg

Nadezhda S. Davidova

Ural State Medical University

Email: davidovaeka@mail.ru
ORCID iD: 0000-0001-7842-6296
SPIN-code: 3766-8337

Dr. Sci. (Med.), Professor, Department of Anesthesiology, Intensive Care

Russian Federation, 32, S. Deryabinoi st., Yekaterinburg, 620149

References

  1. Ratnavel N. Evaluating and improving neonatal transport services. Early Hum Dev. 2013;89(11):851–853. doi: 10.1016/j.earlhumdev.2013.09.004
  2. Karagol BS, Zenciroglu A, Ipek MS, et al. Impact of land-based neonatal transport on outcomes in transient tachypnea of the newborn. Am J Perinatol. 2011;28(4):331–336. doi: 10.1055/s-0030-1270115
  3. Helenius K, Longford N, Lehtonen L, et al.; Neonatal Data Analysis Unit and the United Kingdom Neonatal Collaborative. Association of early postnatal transfer and birth outside a tertiary hospital with mortality and severe brain injury in extremely preterm infants: observational cohort study with propensity score matching. BMJ. 2019;367:l5678. doi: 10.1136/bmj.l5678
  4. Vanevskii VL, Ivaneev MD. Mezhgospital’naya transportirovka detei, nakhodyashchikhsya v kriticheskom sostoyanii, v usloviyakh Leningradskoi oblasti. Russian Journal of Anaesthesiology and Reanimatology. 1989;(6):60–62. (In Russ.)
  5. Shmakov AN, Kokhno VN. Kriticheskie sostoyaniya novorozhdennykh (tekhnologiya distantsionnogo konsul’tirovaniya i ehvakuatsii). Novosibirsk: IPK BIONT, 2007. 168 P. (In Russ.)
  6. Morozova NYa, Yakirevich IA, Popov AS, et al. Sanitary aviation emergency medical care for children in the neonatal period. Neonatology. News, Opinions, Training. 2017;15(1):39–46. (In Russ.)
  7. Bushtyrev VA, Laura NB, Zakharova NI. The score rating of the health status of premature neonatal infants with perinatal infections. Russian Bulletin of perinatology and pediatrics. 2006;51(3):11–15. (In Russ.)
  8. Bushtyrev VA, Budnik ES, Kuznetsova NB. Transportability criteria for premature newborn infant. Obstetrics and Gynecology. 2015;(7):74–77. (In Russ.)
  9. Bushtyrev VA, Zemlyanskaya NV, Petrenko YuV. Transportirovka nuzhdaetsya v pravilakh. StatusPraesens. Pediatriya i neonatologiya. 2017;36(1):71–75. (In Russ.)
  10. Ermachenko MF, Gvak GV, Popelkov AA, et al. Practical justification of the need to develop a new classification of the risk of neonatal transportation. The Doctor. 2020;31(12):85–87. (In Russ.) doi: 10.29296/25877305-2020-12-19
  11. Flabouris A, Runciman WB, Levings B. Incidents during out-of-hospital patient transportation. Anaesth Intensive Care. 2006;34(2):228–236. doi: 10.1177/0310057X0603400216
  12. Lim MT, Ratnavel N. A prospective review of adverse events during interhospital transfers of neonates by a dedicated neonatal transfer service. Pediatr Crit Care Med. 2008;9(3):289–293. doi: 10.1097/PCC.0b013e318172dbfd
  13. Ramnarayan P. Measuring the performance of an inter-hospital transport service. Arch Dis Child. 2009;94(6):414–416. doi: 10.1136/adc.2008.147314
  14. Barry PW, Ralston C. Adverse events occurring during interhospital transfer of the critically ill. Arch Dis Child. 1994;71(1):8–11. doi: 10.1136/adc.71.1.8
  15. Bellini C, de Biasi M, Gente M, et al. Neonatal Transport Study Group of the Italian Society of Neonatology (Società Italiana di Neonatologia, SIN). Rethinking the neonatal transport ground ambulance. Ital J Pediatr. 2019;45(1):97. doi: 10.1186/s13052-019-0686-y
  16. Gente M, Aufieri R, Agostino R, et al. Neonatal Transport Study Group of the Italian Society of Neonatology (SIN). Nationwide survey of neonatal transportation practices in Italy. Ital J Pediatr. 2019;45(1):51. doi: 10.1186/s13052-019-0640-z
  17. Moss SJ, Embleton ND, Fenton AC. Towards safer neonatal transfer: the importance of critical incident review. Arch Dis Child. 2005;90(7):729–732. doi: 10.1136/adc.2004.066639
  18. Kerrey BT, Rinderknecht AS, Geis GL, et al. Rapid sequence intubation for pediatric emergency patients: higher frequency of failed attempts and adverse effects found by video review. Ann Emerg Med. 2012;60(3):251–259. doi: 10.1016/j.annemergmed.2012.02.013
  19. Schmölzer GM, O’Reilly M, Davis PG, et al. Confirmation of correct tracheal tube placement in newborn infants. Resuscitation. 2013;84(6):731–737. doi: 10.1016/j.resuscitation.2012.11.028
  20. Sanchez-Pinto N, Giuliano JS, Schwartz HP, et al. The impact of postintubation chest radiograph during pediatric and neonatal critical care transport. Pediatr Crit Care Med. 2013;14(5):e213–217. doi: 10.1097/PCC.0b013e3182772e13
  21. Smith KA, Gothard MD, Schwartz HP, et al. Risk Factors for Failed Tracheal Intubation in Pediatric and Neonatal Critical Care Specialty Transport. Prehosp Emerg Care. 2015;19(1):17–22. doi: 10.3109/10903127.2014.964888
  22. Wu PL, Lee WT, Lee PL, Chen HL. Predictive Power of Serial Neonatal Therapeutic Intervention Scoring System Scores for Short-term Mortality in Very-low-birth-weight Infants. Pediatrics and Neonatology. 2015;56(2):108–113. doi: 10.1016/j.pedneo.2014.06.005 1875-9572
  23. Lucas da Silva PS, Euzébio de Aguiar V, Reis ME. Assessing Outcome in Interhospital Infant Transport: The Transport Risk Index of Physiologic Stability Score at Admission. Am J Perinatol. 2012;29(7):509–514. doi: 10.1055/s-0032-1310521
  24. Flabouris A, Runciman WB, Levings B. Incidents during out-of-hospital patient transportation. Anaesth Intensive Care. 2006;34(2):228–236. doi: 10.1177/0310057X0603400216

Supplementary files

Supplementary Files
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1. JATS XML
2. Figure. Comparison of ROC curves of the KSCHONN, NTISS and TRIPS scales for daily mortality

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